|
Variables
|
NLR <2.3 (N = 371)
|
p Value
|
2.3 ≤ NLR ≤ 3.4 (N = 375)
|
p Value
|
NLR >3.4 (N = 380)
|
p Value
|
|---|
| |
Sternotomy CABG
|
MICS
| |
Sternotomy CABG
|
MICS
| |
Sternotomy CABG
|
MICS
| |
|---|
|
n
|
242
|
129
| |
245
|
130
| |
243
|
137
| |
|
Age (years)
|
62.5 ± 10.2
|
60.7 ± 10.9
|
0.12
|
64.3 ± 11.0
|
62.6 ± 10.7
|
0.14
|
67.5 ± 11.0
|
65.6 ± 10.7
|
0.10
|
|
Male
|
174 (71.9%)
|
90 (69.8%)
|
0.67
|
172 (70.5%)
|
93 (71.0%)
|
0.92
|
178 (73.3%)
|
100 (73.0%)
|
0.96
|
|
Race (Caucasian)
|
200 (82.6%)
|
106 (82.2%)
|
0.09
|
218 (89.3%)
|
123 (93.9%)
|
0.14
|
227 (93.4%)
|
128 (93.4%)
|
1.00
|
|
Body Mass Index (kg/m2)
|
29.1 ± 5.09
|
29.4 ± 5.42
|
0.65
|
30.0 ± 5.70
|
29.9 ± 6.22
|
0.95
|
28.8 ± 5.50
|
28.7 ± 5.71
|
0.81
|
|
Death
|
21 (8.7%)
|
9 (7.0%)
|
0.57
|
32 (13.1%)
|
17 (13.0%)
|
0.97
|
57 (23.5%)
|
18 (13.1%)
|
0.02
|
|
Family history of CAD
|
101 (41.7%)
|
63 (48.8%)
|
0.19
|
79 (32.4%)
|
45 (34.4%)
|
0.7
|
89 (36.6%)
|
41 (29.9%)
|
0.19
|
|
Smoking
|
149 (62.9%)
|
65 (50.4%)
|
0.02
|
141 (59.7%)
|
72 (55.4%)
|
0.42
|
134 (55.6%)
|
69 (50.4%)
|
0.33
|
|
Hypertension
|
172 (71.1%)
|
98 (76.6%)
|
0.26
|
180 (74.1%)
|
93 (71.0%)
|
0.52
|
181 (74.5%)
|
113 (83.1%)
|
0.05
|
|
Diabetes mellitus
|
94 (38.8%)
|
33 (25.6%)
|
0.01
|
73 (29.9%)
|
33 (25.2%)
|
0.33
|
96 (39.5%)
|
47 (34.3%)
|
0.32
|
|
Peripheral arterial disease
|
29 (12.0%)
|
13 (10.1%)
|
0.58
|
36 (14.8%)
|
7 (5.3%)
|
0.006
|
39 (16.0%)
|
14 (10.2%)
|
0.12
|
|
Renal failure on dialysis
|
3 (1.2%)
|
1 (0.8%)
|
0.68
|
3 (1.2%)
|
5 (3.8%)
|
0.1
|
8 (3.3%)
|
9 (6.6%)
|
0.14
|
|
Myocardial infarction
|
134 (55.4%)
|
51 (39.5%)
|
0.004
|
132 (54.1%)
|
52 (39.7%)
|
0.008
|
130 (53.5%)
|
38 (27.7%)
|
<0.001
|
|
History of PCI
|
71 (29.3%)
|
23 (17.8%)
|
0.02
|
66 (27.0%)
|
31 (23.7%)
|
0.48
|
58 (23.9%)
|
23 (16.8%)
|
0.11
|
|
Prior CABG
|
7 (2.9%)
|
2 (1.6%)
|
0.51
|
7 (2.9%)
|
1 (0.8%)
|
0.27
|
9 (3.7%)
|
2 (1.5%)
|
0.34
|
|
Prior heart failure
|
37 (15.3%)
|
7 (5.4%)
|
0.005
|
41 (16.8%)
|
9 (6.9%)
|
0.007
|
45 (18.5%)
|
11 (8.0%)
|
0.01
|
|
Prior cerebrovascular event
|
31 (12.8%)
|
8 (6.2%)
|
0.048
|
39 (16.0%)
|
11 (8.4%)
|
0.04
|
50 (20.6%)
|
12 (8.8%)
|
0.003
|
|
C0PD
|
30 (12.4%)
|
10 (7.9%)
|
0.18
|
34 (13.9%)
|
16 (12.2%)
|
0.64
|
34 (14.0%)
|
16 (11.7%)
|
0.52
|
|
Preoperative CCS
| | | | | | | | | |
|
none
|
0 (0%)
|
1 (0.8%)
|
0.14
|
2 (0.8%)
|
0 (0%)
|
0.02
|
2 (0.8%)
|
0 (0%)
|
<0.001
|
|
Class I
|
42 (17.6%)
|
24 (18.6%)
| |
34 (13.9%)
|
32 (24.4%)
| |
41 (17.2%)
|
28 (20.6%)
| |
|
Class II
|
61 (25.5%)
|
45 (34.9%)
| |
74 (30.3%)
|
47 (35.9%)
| |
46 (19.3%)
|
49 (36.0%)
| |
|
Class III
|
68 (28.5%)
|
33 (25.6%)
| |
75 (30.7%)
|
29 (22.1%)
| |
83 (34.9%)
|
45 (33.1%)
| |
|
Class IV
|
68 (28.5%)
|
26 (20.2%)
| |
59 (24.2%)
|
23 (17.6%)
| |
66 (27.7%)
|
14 (10.3%)
| |
|
NYHA
| | | | | | | | | |
|
Class I
|
22 (17.9%)
|
21 (19.4%)
|
0.21
|
25 (29.2%)
|
25 (24.0%)
|
0.31
|
30 (23.8%)
|
22 (21.2%)
|
0.03
|
|
Class II
|
33 (26.8%)
|
40 (37.0%)
| |
42 (32.3%)
|
39 (37.5%)
| |
26 (20.6%)
|
33 (31.7%)
| |
|
Class III
|
44 (35.8%)
|
26 (24.1%)
| |
37 (28.5%)
|
19 (18.3%)
| |
38 (30.2%)
|
37 (35.6%)
| |
|
Class IV
|
24 (19.5%)
|
21 (19.4%)
| |
26 (20.0%)
|
21 (20.2%)
| |
32 (25.4%)
|
12 (11.5%)
| |
|
Ejection Fraction (%)
|
39.8 ± 12.1
|
41.0 ± 10.8
|
0.32
|
39.1 ± 12.1
|
41.6 ± 10.4
|
0.04
|
39.3 ± 12.8
|
41.2 ± 12.4
|
0.17
|
|
Preoperative laboratory values
| | | | | | | | | |
|
Leukocyte (k/cc)
|
7.42 ± 2.31
|
7.20 ± 2.03
|
0.37
|
8.09 ± 2.22
|
7.61 ± 2.20
|
0.05
|
9.70 ± 3.13
|
8.87 ± 2.71
|
0.01
|
|
Neutrophils (k/cc)
|
4.06 ± 1.35
|
3.94 ± 1.29
|
0.40
|
5.28 ± 1.55
|
4.97 ± 1.51
|
0.06
|
7.45 ± 2.82
|
6.76 ± 2.45
|
0.01
|
|
Lymphocytes (k/cc)
|
2.45 ± 1.10
|
2.40 ± 0.763
|
0.40
|
1.91 ± 0.566
|
1.79 ± 0.533
|
0.06
|
1.35 ± 0.462
|
1.29 ± 0.455
|
0.24
|
|
Monocytes (k/cc)
|
0.62 ± 0.286
|
0.62 ± 0.241
|
0.80
|
0.65 ± 0.263
|
0.60 ± 0.225
|
0.12
|
0.69 ± 0.299
|
0.62 ± 0.237
|
0.02
|
|
Creatinine (mg/dl)
|
1.06 ± 0.741
|
1.07 ± 0.983
|
0.99
|
1.14 ± 0.711
|
1.19 ± 1.02
|
0.56
|
1.26 ± 0.61
|
1.18 ± 0.604
|
0.06
|
|
Glucose (mg/dl)
|
124.0 ± 48.9
|
122.4 ± 52.4
|
0.76
|
126.1 ± 49.3
|
110.8 ± 41.6
|
0.002
|
136.2 ± 58.8
|
121.5 ± 46.3
|
0.01
|
-
CABG coronary artery bypass grafting, CAD coronary artery disease, CCS Canadian Cardiovascular Society Angina classification system, COPD chronic obstructive pulmonary disease, NYHA New York Heart Association Functional Classification, PCI percutaneous coronary intervention. Categorical variables were presented as frequencies and percentages; continuous variables were presented as means and standard deviations.
