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Table 2 Relapse free survival - univariate analysis

From: Recurrence risk after Ivor Lewis oesophagectomy for cancer

Preoperative data

% 5-y RFS (n) (n total = 120)

p

Age (years) : <60 / >60

58.6 (16) / 45.6 (37)

0.0396

ASA score : 1-2 / 3

50.0 (41) / 55.1 (12)

0.6742

Sex : Male / Female

48.5 (46) / 61.8 (7)

0.1641

Histology : Adenocarcinoma / Squamous cell carcinoma

53.9 (34) / 43.0 (19)

0.7995

Weight loss (%) : ≤ 10 / > 10

56.3 (38) / 29.2 (15)

0.0379

Body Mass Index (Kg/m2) : ≤ 25 / > 25

51.2 (32) / 49.4 (21)

0.597

Gastro-oesophageal reflux disease : No / Yes

45.5 (36) / 60.4 (17)

0.2185

Tumor stenosis : No / Yes

77.9 (11) / 31.8 (42)

<0.0001

TDM pathological lymph node : No / Yes

56.0 (37) / 33.7 (16)

0.063

EUS results

  

usT : 1&2 / 3&4

72.5 (9) / 52.0 (11)

0.1727

usN : 0 / 1

78.1 (4) / 51.7 (16)

0.0227

Preoperative treatment : No / CT or CRT

51.9 (37) / 49.2 (16)

0.7166

Tumor localization : Oesophagogastric jct. / Lower or mid third

40.2 (18) / 58.9 (35)

0.0046

Postoperative data

% 5-y RFS (n)

p

Differentiation: Undiff. or poorly diff. / Moderately or well diff.

40.9 (13) / 55.6 (35)

0.0313

pT Stage : T ≤ 2 / T > 2

75.9 (13) / 24.9 (40)

<0.0001

pN Stage : N0 / N+

82.9 (9) / 16.7 (44)

<0.0001

Resection : R0 / R1 or R2

57.2 (37) / 25.0 (16)

0.002

Circumferential margin : Complete / Incomplete

56.9 (39) / 19.6 (14)

0.0019

Node capsular penetration : No/Yes

52.4 (49) / 20.0 (4)

0.0206

Angiolymphatic invasion : No / Yes

66.4 (17) / 19.4 (29)

<0.0001

Neural invasion : No / Yes

66.5 (16) / 25.5 (28)

<0.0001

Number of positive lymph nodes : 0 / 1-4 / >4

82.9 (9) / 23.4 (23) / 7.8 (21)

<0.0001

Lymph node ratio : ≤ 0.2 / > 0.2

66.5 (26) / 0.0 (27)

<0.0001