From: Recurrence risk after Ivor Lewis oesophagectomy for cancer
Preoperative data | % 5-y RFS (n) (n total = 120) | p |
---|---|---|
Age (years) : <60 / >60 | 58.6 (16) / 45.6 (37) | 0.0396 |
ASA score : 1-2 / 3 | 50.0 (41) / 55.1 (12) | 0.6742 |
Sex : Male / Female | 48.5 (46) / 61.8 (7) | 0.1641 |
Histology : Adenocarcinoma / Squamous cell carcinoma | 53.9 (34) / 43.0 (19) | 0.7995 |
Weight loss (%) : ≤ 10 / > 10 | 56.3 (38) / 29.2 (15) | 0.0379 |
Body Mass Index (Kg/m2) : ≤ 25 / > 25 | 51.2 (32) / 49.4 (21) | 0.597 |
Gastro-oesophageal reflux disease : No / Yes | 45.5 (36) / 60.4 (17) | 0.2185 |
Tumor stenosis : No / Yes | 77.9 (11) / 31.8 (42) | <0.0001 |
TDM pathological lymph node : No / Yes | 56.0 (37) / 33.7 (16) | 0.063 |
EUS results | ||
usT : 1&2 / 3&4 | 72.5 (9) / 52.0 (11) | 0.1727 |
usN : 0 / 1 | 78.1 (4) / 51.7 (16) | 0.0227 |
Preoperative treatment : No / CT or CRT | 51.9 (37) / 49.2 (16) | 0.7166 |
Tumor localization : Oesophagogastric jct. / Lower or mid third | 40.2 (18) / 58.9 (35) | 0.0046 |
Postoperative data | % 5-y RFS (n) | p |
Differentiation: Undiff. or poorly diff. / Moderately or well diff. | 40.9 (13) / 55.6 (35) | 0.0313 |
pT Stage : T ≤ 2 / T > 2 | 75.9 (13) / 24.9 (40) | <0.0001 |
pN Stage : N0 / N+ | 82.9 (9) / 16.7 (44) | <0.0001 |
Resection : R0 / R1 or R2 | 57.2 (37) / 25.0 (16) | 0.002 |
Circumferential margin : Complete / Incomplete | 56.9 (39) / 19.6 (14) | 0.0019 |
Node capsular penetration : No/Yes | 52.4 (49) / 20.0 (4) | 0.0206 |
Angiolymphatic invasion : No / Yes | 66.4 (17) / 19.4 (29) | <0.0001 |
Neural invasion : No / Yes | 66.5 (16) / 25.5 (28) | <0.0001 |
Number of positive lymph nodes : 0 / 1-4 / >4 | 82.9 (9) / 23.4 (23) / 7.8 (21) | <0.0001 |
Lymph node ratio : ≤ 0.2 / > 0.2 | 66.5 (26) / 0.0 (27) | <0.0001 |