Figure 1

Hemodynamic parameters in the isolated rat hearts subjected to global ischemia under either a hypothermic or normothermic condition (22°C or 37°C, respectively) followed by 120 min of normothermic reperfusion. Ischemic contracture in the hypothermia (A) and normothermia series (B); left ventricular developed pressure (LVDP) in the hypothermia (C) and normothermia series (D); and left ventricular end-diastolic pressure (LVEDP) in the hypothermia (E) and normothermia series (F). Group legends in the hypothermia series: the controls subjected to 180-min ischemia and 120-min reperfusion (CON-22), cardioplegia with the modified Krebs-Henseleit buffer-based cardioplegic solution (mKHB-22), and cardioplegia with St. Thomas’ Hospital cardioplegic solution No. 2 (STH2-22). Group legends in the normothermia series: controls subjected to 60-min ischemia and 120-min reperfusion (CON-37), cardioplegia with the modified Krebs-Henseleit buffer-based cardioplegic solution (mKHB-37), and cardioplegia with St. Thomas’ Hospital cardioplegic solution No. 2 (STH2-37). BL, baseline values. The data are the mean ± SD values. *P < 0.01; **P < 0.001; ^& P < 0.05; ^# P < 0.001; ^§ P < 0.0001; ^¶ P < 0.0001; ^† P < 0.001.