Aortic stiffness as a marker of cardiac function and myocardial strain in patients undergoing aortic valve replacement

Table 5 Multiple linear regression to identify predictors of the myocardial strain biomarker BNP

Predictors	BNP (pre-op.)^A	BNP (3 h post-CPB)^A	BNP (18 h post-CPB)^A
Model 1
PWV value	0.06	0.11	0.18
PWV value	(0.72)	(0.51)	(0.29)
Age	0.26	0.29	0.01
Age	(0.11)	(0.09)	(0.95)
Gender (male)	-0.20	-0.38	-0.12
Gender (male)	(0.15)	(0.0.1)	(0.43)
MAP	-0.36
MAP	(0.01)
DM			-0.30
DM			(0.05)
Model 2
PWV cut-off	0.20	0.09	0.32
(PWV-high)	(0.14)	(0.51)	(0.03)
Age	0.27	0.21	0.06
Age	(0.05)	(0.14)	(0.65)
Gender (male)	-0.17	-0.34	-0.09
Gender (male)	(0.22)	(0.02)	(0.51)
MAP	-0.35
MAP	(0.01)
DM			-0.33
DM			(0.03)

Values are shown as beta (P-value), bold values indicate statistical significance; ^ALog transformation. Model 1 includes PWV value as a continuous predictor; Model 2 includes PWV cut-off as a dichotomous predictor. Abbreviations: DM diabetes mellitus, MAP mean arterial blood pressure, PWV pulse wave velocity, BNP B-type natriuretic peptides.

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