Table 1 The goals of GDRRT

Solute

BUN ≤ 30 mmol/L

Volume

Urine output ≥ 0.5 ml/kg/h, 24 h fluid output ≥ 24 h fluid intake in volume overload patients, controlled acute pulmonary edema, reduction of peripheral edema, hematocrit ≥ 30%

Electrolyte and pH

Electrolyte and acid-base parameters normal or near normal: 3.5 < potassium ≤ 5.5 mmol, 7.25 ≤ pH < 7.45

Hemodynamics

MAP ≥ 65 mmHg without vasoactive drugs, CVP ≥ 8–12 mmHg, SaO₂ ≥ 93%