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Figure 5 | Journal of Cardiothoracic Surgery

Figure 5

From: The Na+/Ca2+ exchange inhibitor SEA0400 limits intracellular Ca2+ accumulation and improves recovery of ventricular function when added to cardioplegia

Figure 5

Effect of SEA0400 in cardioplegia on cell shortening in isolated cardiomyoyctes. Graph of cell shortening (contraction amplitude) measured using video edge detection. Points represent mean ± SEM, n = 25 (cardioplegia with SEA0400), 24 (cardioplegia without SEA0400), and 8 (no cardioplegia). All values are normalized to the time point immediately prior to ischemia (20 min). ϕ = <0.01, # = p < 0.001 vs. cardioplegia with SEA0400.

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