Activated coagulation time vs. intrinsically activated modified rotational thromboelastometry in assessment of hemostatic disturbances and blood loss after protamine administration in elective cardiac surgery: analysis from the clinical trial (NCT01281397)

Table 3 Differences in activated coagulation time (ACT) and Intrinsically activated modified rotational thromboelastometry (InTEM) parameters of patient groups according to bleeding tendency

	C.T.O. Overall (mL)	N	Median	Interquartile range	P (Mann–Whitney U)
INTEM CT	Non-bleeder	111	194,00	171,00-214,00	0.379
INTEM CT	Bleeder	37	198,00	182,00-221,00	0.379
INTEM CFT	Non-bleeder	111	124,00	98,00-165,00	0.033
INTEM CFT	Bleeder	37	149,00	103,50-207,50	0.033
INTEM ALFA ANGLE (degrees)	Non-bleeder	111	69,00	64,00-74,00	0.016
INTEM ALFA ANGLE (degrees)	Bleeder	37	65,00	56,50-72,00	0.016
INTEM MCF	Non-bleeder	111	55,00	50,00-59,00	0.017
INTEM MCF	Bleeder	37	51,00	46,00-57,00	0.017
INTEM A10	Non-bleeder	111	46,00	41,00-50,00	0.013
INTEM A10	Bleeder	37	41,00	36,00-48,50	0.013
INTEM A20	Non-bleeder	111	53,00	48,00-57,00	0.016
INTEM A20	Bleeder	37	49,00	44,00-54,50	0.016
INTEM A30	Non-bleeder	111	55,00	50,00-59,00	0.018
INTEM A30	Bleeder	37	51,00	46,50-56,50	0.018
Activated coagulation time after protamine administration (sec)	Non-bleeder	111	138,00	127,00-145,00	0.179
	Bleeder	37	141,00	131,50-149,50	0.179