Figure 4

Immunohistochemistry of proximal, middle, and distal LAD. A: Representative photomicrographs of brown immunostaining for T-Cadherin [A, upper panels], SRA [B, middle panels] and Adiponectin [C, lower panels] in the designated LAD segments. Arrows point to brown positive stains in the endothelial and sub-endothelial neo-intima for each marker. Scale bar = 500 microns. B: Percent immunohistochemical staining of the proximal, middle and distal 15 mm segments of left anterior descending coronary wall intima-media for a; T-Cadherin, b; SRA and c; adiponectin. The same letters (a-a, b-b) indicate that the mean ± sem in the segments are significantly different (n = 8 separate samples from each segment, p < 0.05).