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Table 2 Clinical and analytical parameters from patients undergoing CABG whose pre-surgical sera were used for the study

From: Age-dependent defective TGF-beta1 signaling in patients undergoing coronary artery bypass grafting

 

<55

55-64

65-74

>75

P

Number

23

48

61

31

 

Age

49.61

59.75

69.08

76.77

P < 0.0001*

Sex (% men)

23 (100%)

42 (87.5%)

52 (85.24%)

17 (56.67%)

0.0002

BMI

26.70 ± 0.643

27.58 ± 0.504

27.60 ± 0.458

27.13 ± 0.645

0.8639*

EF

58.52 ± 3.311

59.83 ± 2.000

59.95 ± 1.822

59.71 ± 2.049

0.4084*

Tobacco

10 (43.48%)

13 (27.08%)

12 (17.64%)

4 (12.90%)

0.0065

Alcohol

13 (56.52%)

29 (60.42%)

33 (54.10%)

6 (12.90%)

0.0023

Hypertension

7 (30.43%)

22 (45.83%)

40 (65.57%)

20 (64.52%)

0.012

Dyslipemia

12 (52.17%)

30 (62.50%)

27 (44.26%)

16 (51.61%)

0.2871*

DM

5 (23.74%)

18 (37.50%)

20 (32.79%)

17 (54.84%)

0.0958

IM < 30 days

11 (47.83%)

24 (50%)

35 (57.38%)

16 (51.61%)

0.7676

Creatinine

1.030 ± 0.027

1.060 ± 0.024

1.130 ± 0.027

1.131 ± 0.045

0.0765*

Leukocytes

7854 ± 343.3

7592 ± 272

7466 ± 250.8

7120 ± 406.5

0.5640*

Monocytes

635.7 ± 41.40

612.6 ± 33.45

600.0 ± 24.63

617.7 ± 33.16

0.9078*

Platelets

227000 ± 12379

241128 ± 10477

224164 ± 7085

234452 ± 14260

0.5895*

TGF-β

42.21 ± 2.715

41.87 ± 2.187

36.44 ± 1.669

33.35 ± 2.092

0.0157*

TGF-β/platelet*1000

0.1937 ± 0.0129

0.1842 ± 0.0121

0.1684 ± 0.008

0.1583 ± 0.013

0.2220*

  1. *One-way ANOVA. Chi-squared test.
  2. BMI: body mass index. EF: Ejection fraction. DM: diabetes mellitus. IM < 30 days: myocardial infarction within 30 days before surgery.