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Table 1 The baseline clinical characteristics and laboratory parameters of the patients

From: The effects of a low international normalized ratio on thromboembolic and bleeding complications in patients with mechanical mitral valve replacement

Variables

Group 1 n = 34

Group 2 n = 49

Group 3 n = 52

*F

*p

Age, years

55.9 ± 12.9

49.9 ± 13.2

50.1 ± 14.2

2.428

0.092

Gender, male (%)

23 (67.6)

33 (67.3)

30 (57.7)

-

0.516

Atrial fibrillation, n (%)

17 (50)

28 (57.1)

26 (50)

-

0.727

Hypertension, n (%)

16 (47.1)

14 (28.6)

19 (36.5)

-

0.227

Diabetes mellitus, n (%)

8 (23.5)

5 (10.2)

4 (7.7)

-

0.079

Smoking, n (%)

5 (20)

15 (32.6)

11 (21.6)

-

0.360

Neurological dysfunction, n (%)

3 (8.8)

3 (6.1)

2 (3.8)

-

0.632

Follow-up time, months

33.7 ± 29.0

40.4 ± 32.9

42.8 ± 31.5

0.884

0.416

Mean LVEF, %

53.3 ± 9.8

53.2 ± 8.8

54.0 ± 9.2

0.778

0.461

Left atrium, cm

5.2 ± 0.8

5.8 ± 1.0

5.5 ± 1.0

3.727

0.027

sPAP, mmHg

40.8 ± 12.7

43.8 ± 14.7

42.2 ± 12.5

0.506

0.604

Hemoglobin, g/dL

13.6 ± 1.5

12.7 ± 1.6

12.3 ± 1.3

7.899

0.001

WBC, ×103/μL

7.8 ± 2.7

8.5 ± 2.2

7.7 ± 1.9

2.098

0.127

Platelet, ×103/μL

196.91 ± 68.1

218.98 ± 77.7

231.77 ± 78.4

2.181

0.117

Creatinine, mg/dL

1.24 ± 1.3

1.39 ± 1.5

0.9 ± 0.2

2.201

0.115

Mean INR level

1.8 ± 0.1

2.2 ± 0.1

2.8 ± 0.3

232.346

<0.001

  1. INR: International Normalized Ratio, LVEF: Left Ventricle Ejection Fraction, sPAP: Systolic Pulmonary Arterial Pressure, WBC: White Blood Cell.
  2. *Chi-square and ANOVA with posthoc Tukey test.