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Table 3 Univariate analysis for presence of any thromboembolic or bleeding events

From: The effects of a low international normalized ratio on thromboembolic and bleeding complications in patients with mechanical mitral valve replacement

 

Patients with TEs N: 10

Patients without TEs N: 125

P value

Patients with bleeding events N: 12

Patients without bleeding events N: 123

P value

Age, years

49.3 ± 13.8

51.7 ± 13.7

0.600

48.0 ± 9.1

51.8 ± 14.1

0.356

Gender, male (%)

4 (40.0)

45 (36.0)

1.0

4 (33.3)

45 (36.6)

1.0

Atrial fibrillation, n (%)

8 (80)

63 (50.4)

0.101

7 (58.3)

64 (52)

0,768

Hypertension, n (%)

5 (50)

44 (35.2)

0.496

4 (33.3)

45 (36.6)

1.0

Diabetes mellitus, n (%)

0

17 (13.6)

0.361

1 (8.3)

16 (13)

1.0

Smoking, n (%)

3 (37.5)

28 (24.6)

0.418

4 (33.3)

27 (24.5)

0.498

Neurological dysfunction, n (%)

2 (20)

6 (4.8)

0.109

3 (25)

5 (4.1)

0.024

Follow-up Time, months

47.1 ± 30.7

39.0 ± 30.5

0.439

53.2 ± 39.4

38.3 ± 30.4

0.117

Mean LVEF, %

55.9 ± 10.2

53.9 ± 9.1

0.514

54.0 ± 12.9

54.0 ± 8.9

0.984

Left Atrium, cm

5.6 ± 1.1

5.5 ± 1.0

0.799

5.7 ± 0.9

5.5 ± 1.0

0.642

sPAP, mmHg

44.1 ± 12.9

42.3 ± 13.5

0.692

41.9 ± 12.5

42.5 ± 13.5

0.881

Hemoglobin, g/dL

12.7 ± 1.1

13.0 ± 1.6

0.512

13.2 ± 1.4

13.0 ± 1.7

0.587

Platelet, ×103/μL

211 ± 63

218 ± 77

0.769

259 ± 57

214 ± 76

0.051

Creatinine, mg/dL

0.8 ± 0.2

1.2 ± 1.2

0.283

0.9 ± 0.2

1.2 ± 1.2

0.457

Mean INR level

2.1 ± 0.4

2.4 ± 0.5

0.022

2.4 ± 0.4

2.7 ± 0.5

0.016

  1. INR: International Normalized Ratio, LVEF: Left Ventricle Ejection Fraction, sPAP: Systolic Pulmonary Arterial Pressure, TEs: Thromboembolic events.
  2. Data are presented as number (percentage) and mean ± SD values.
  3. Chi-square, unpaired Student-t test and the Mann–Whitney U test.