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Table 3 Univariate analysis for presence of any thromboembolic or bleeding events

From: The effects of a low international normalized ratio on thromboembolic and bleeding complications in patients with mechanical mitral valve replacement

  Patients with TEs N: 10 Patients without TEs N: 125 P value Patients with bleeding events N: 12 Patients without bleeding events N: 123 P value
Age, years 49.3 ± 13.8 51.7 ± 13.7 0.600 48.0 ± 9.1 51.8 ± 14.1 0.356
Gender, male (%) 4 (40.0) 45 (36.0) 1.0 4 (33.3) 45 (36.6) 1.0
Atrial fibrillation, n (%) 8 (80) 63 (50.4) 0.101 7 (58.3) 64 (52) 0,768
Hypertension, n (%) 5 (50) 44 (35.2) 0.496 4 (33.3) 45 (36.6) 1.0
Diabetes mellitus, n (%) 0 17 (13.6) 0.361 1 (8.3) 16 (13) 1.0
Smoking, n (%) 3 (37.5) 28 (24.6) 0.418 4 (33.3) 27 (24.5) 0.498
Neurological dysfunction, n (%) 2 (20) 6 (4.8) 0.109 3 (25) 5 (4.1) 0.024
Follow-up Time, months 47.1 ± 30.7 39.0 ± 30.5 0.439 53.2 ± 39.4 38.3 ± 30.4 0.117
Mean LVEF, % 55.9 ± 10.2 53.9 ± 9.1 0.514 54.0 ± 12.9 54.0 ± 8.9 0.984
Left Atrium, cm 5.6 ± 1.1 5.5 ± 1.0 0.799 5.7 ± 0.9 5.5 ± 1.0 0.642
sPAP, mmHg 44.1 ± 12.9 42.3 ± 13.5 0.692 41.9 ± 12.5 42.5 ± 13.5 0.881
Hemoglobin, g/dL 12.7 ± 1.1 13.0 ± 1.6 0.512 13.2 ± 1.4 13.0 ± 1.7 0.587
Platelet, ×103/μL 211 ± 63 218 ± 77 0.769 259 ± 57 214 ± 76 0.051
Creatinine, mg/dL 0.8 ± 0.2 1.2 ± 1.2 0.283 0.9 ± 0.2 1.2 ± 1.2 0.457
Mean INR level 2.1 ± 0.4 2.4 ± 0.5 0.022 2.4 ± 0.4 2.7 ± 0.5 0.016
  1. INR: International Normalized Ratio, LVEF: Left Ventricle Ejection Fraction, sPAP: Systolic Pulmonary Arterial Pressure, TEs: Thromboembolic events.
  2. Data are presented as number (percentage) and mean ± SD values.
  3. Chi-square, unpaired Student-t test and the Mann–Whitney U test.