Pulse wave velocity and neutrophil gelatinase-associated lipocalin as predictors of acute kidney injury following aortic valve replacement

Table 3 Levels of the renal function markers at different study time-points

Marker	Total	AKI-No	AKI-Yes	P-value	Intervention-No	Intervention-Yes	P-value
Marker	n = 53	n = 37	n = 16	P-value	n = 29	n = 24	P-value
Creatinine (μmol/L)
Pre-operative	80 ± 14	79 ± 14	82 ± 12	0.25	76 ± 11	85 ± 14	0.02
3 h post-CPB	71 ± 15	68 ± 13	77 ± 19	0.12	69 ± 13	73 ± 18	0.44
18 h post-CPB	87 ± 35	74 ± 17	116 ± 45	<0.001	73 ± 16	103 ± 43	<0.01
GFR (ml/min/1.73 m ² )
Pre-operative	80 ± 17	80 ± 19	77 ± 13	0.55	86 ± 16	72 ± 15	<0.01
3 h post-CPB	94 ± 19	96 ± 19	88 ± 21	0.32	97 ± 18	89 ± 21	0.22
18 h post-CPB	79 ± 26	88 ± 21	58 ± 24	<0.001	91 ± 19	65 ± 26	<0.001
NGAL (ng/ml)
Pre-operative	80 ± 35	83 ± 40	73 ± 20	0.55	83 ± 40	76 ± 25	0.96
3 h post-CPB	129 ± 61	113 ± 51	167 ± 66	<0.001	100 ± 29	164 ± 70	<0.001
18 h post-CPB	81 ± 38	74 ± 28	98 ± 53	0.02	71 ± 22	94 ± 49	0.01

Values are shown as mean ± standard deviation; bold font indicates significant values. Abbreviations: CPB, cardiopulmonary bypass; GFR, glomerular filtration rate (Modification of Diet in Renal Disease equation); NGAL, neutrophil gelatinase-associated lipocalin.

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