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Table 1 Demographic features of patients

From: Combination use of platelets and recombinant activated factor VII for increased hemostasis during acute type a dissection operations

Variable Control (n = 46) rFVIIa + platelet (n = 25) pValue
Age (years) 52.8 ± 10.3 53.7 ± 11.3 0.724
Male sex 31 (67%) 15 (60%) 0.607
Height (cm) 168.9 ± 8.3 167.3 ± 8.6 0.449
Weight (kg) 69.7 ± 11.8 71.4 ± 11.5 0.587
Body surface area (m2) 1.75 ± 0.16 1.78 ± 0.19 0.647
Baseline laboratory values    
Hemoglobin (g/L) 130 ± 16 130 ± 21 0.979
Platelets counts (109cells/L) 172 ± 70 161 ± 53 0.499
International normalized ratio (INR) 1.00 ± 0.10 0.98 ± 0.09 0.305
Activated partial thromboplastin time (APTT) (sec) 26.6 ± 2.1 28.6 ± 1.0 0.964
Prothrombin time (PT) (sec) 11.9 ± 0.2 11.6 ± 0.2 0.368
D-dimer (ng/ml) 2147.8 ± 512.3 2497.5 ± 532.1 0.642
Creatinine (μmol/L) 83.1 ± 20.6 87.1 ± 32.7 0.554
ASA class    
III 3(6.5%) 1(4.0%) 1
IV 43(93.5%) 24(96.0%) 1
Principal procedure    
Bental 2(4.3%) 0(0%) 0.416
Ascending aortic replacement 3(6.5%) 2(8%) 1
Bental + hemiarch replacement 1(2.2%) 1(4%) 0.584
Ascending aortic + total arch replacement 3(6.5%) 0(0%) 0.492
Bental + total arch replacement + stent implanted 3(6.5%) 1(4%) 1
Ascending aortic + total arch replacement + stent implanted 34(73.9%) 21(84.0%) 0.331
Deep hypothermic circulatory arrest time (min) 49.5 ± 14.6 50.8 ± 11.4 0.711
Selective cerebralperfusion time (min) 43.8 ± 13.2 42.7 ± 11.1 0.724
Selective cerebralperfusion flow rate (ml/min) 492.2 ± 88.3 484.8 ± 93.6 0.743
Cardiopulmonary bypass time (min) 196.3 ± 41.8 191.4 ± 26.7 0.605
Nadir hemoglobin on bypass (g/dL) 7.3 ± 1.2 7.6 ± 0.9 0.267
  1. Values expressed as average (standard deviation) or number (percent). ASA = American Society of Anesthesiologists.