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Table 3 Summary of study secondary endpoints

From: A retrospective analysis of myocardial preservation techniques during coronary artery bypass graft surgery: are we protecting the heart?

Patients

Group 1

Group 2

Group 3

P value

Antegrade cardioplegia

Cross-clamp fibrillation

Antegrade retrograde cardioplegia

(n = 28)

(n = 16)

(n = 10)

(Mean [SD])

(Mean [SD])

(Mean [SD])

AKI (N)

0

22 (79%)

11 (69%)

10 (100.0%)

 

1

5 (18%)

2 (13%)

(0.0%)

 

2

0 (0.0%)

2 (13%)

(0.0%)

 

3

1 (4%)

1 (6%)

(0.0%)

 

Total number of AKI cases

6 (21%)

5 (31%)

0 (0.0%)

0.281*

Inotrope score (mg/kg/hr)

Post bypass

7.24 (13.79)

4.03 (11.92)

3.76 (4.35)

0.816**

24 hours post-operatively

11.90 (21.32)

10.11 (22.88)

3.67 (4.36)

0.635**

48 hours post-operatively

8.76 (15.39)

14.93 (33.57)

1.94 (2.98)

0.101**

72 hours post-operatively

1.85 (5.30)

13.54 (33.13)

2.13 (2.95)

0.015**

Total

29.88 (49.10)

42.54 (94.66)

11.66 (13.79)

0.545***

New onset AF (N)

6 (21%)

5 (31%)

4 (40.0%)

0.475*

Length of ICU stay (days)

2.0 (2.0-4.0)****

3 (1.0-7.5)****

2.0 (1.0-3.0)****

0.802*****

Length of hospital stay (days)

8.5 (7.0-11.50)****

8.0 (6.0-10.50)****

7.5 (6.0-9.00)****

0.523*****

Clinical outcomes at 6 weeks (N)

Death

3 (14%)

0 (0.0%)

0 (0.0%)

0.283*

Myocardial infarction

1 (4%)

0 (0.0%)

0 (0.0%)

1.000*

Stroke

0 (0.0%)

0 (0.0%)

0 (0.0%)

1.000

Revascularization

0 (0.0%)

0 (0.0%)

0 (0.0%)

1.000*

  1. SD = standard deviation AKI = Acute Kidney Injury; AF = atrial fibrillation; ICU = Intensive Care Unit.
  2. *P value for Fisher’s exact test.
  3. **P-value from repeated measures linear regression model.
  4. ***P-value form linear regression model.
  5. ****Results shown as median (inter-quartile range).
  6. *****P-value for Median T test.
  7. The following secondary endpoints had missing values: Inotrope Score post-bypass (Group-1 2, Group-2 2, Group-3 1), Inotrope Score 24 hours post-operatively (Group-1 3, Group-2 2, Group-3 1), Inotrope Score 48 hours post-operatively (Group-1 3, Group-2 2, Group-3 2), Inotrope Score 72 hours post-operatively (Group-1 3, Group-2 2, Group-3 2), Inotrope Score Total (Group-1 3 , Group-2 2, Group-3 2), Length of ICU stay (Group-2 1), Length of Hospital stay (Group-2 1), Death (Group-1 7, Group-2 3, Group-3 2), Myocardial Infarction (Group-1 7, Group-2 3, Group-3 2), Stroke (Group-1 7, Group-2 3, Group-3 2), Revascularization (Group-1 7, Group-2 3, Group-3 2).