Table 2 Serial echocardiographic findings of mitral valve function during systole and diastole

  MR grade

2.6 ± 0.6

3.8 ± 0.4^a

3.7 ± 0.5^a

<0.01

  CD (cm)

0.8 ± 0.2

1.4 ± 0.5^a

1.1 ± 0.1

<0.01

Tethering area (cm ² )

1.5 ± 0.5

2.4 ± 0.6^a

1.9 ± 0.5

<0.01

  MIA (°)

68 ± 8

61 ± 6

68 ± 7

0.076

  α1 (°)

54 ± 10

49 ± 9

55 ± 6

0.32

  α2 (°)

84 ± 17

83 ± 13

83 ± 9

0.99

  L1 (cm)

1.8 ± 0.4

1.8 ± 0.4

1.8 ± 0.1

0.98

  MR grade

0.4 ± 0.6**

0.5 ± 0.5**

0.5 ± 0.5**

0.25

  CD (cm)

0.4 ± 0.2**

0.4 ± 0.1**

0.5 ± 0.3**

0.59

Tethering area (cm ² )

0.6 ± 0.5*

0.4 ± 0.2*

0.7 ± 0.4*

0.41

  MIA (°)

60 ± 9*

42 ± 10^a,c,**

67 ± 6

<0.01

  α1 (°)

55 ± 12

39 ± 9^a,c,*

67 ± 12*

<0.01

  α2 (°)

100 ± 12*

106 ± 22*

85 ± 10^b

0.045

  L1 (cm)

1.4 ± 0.3*

1.1 ± 0.2^a,*

1.3 ± 0.1*

0.012

  MR grade

0.6 ± 0.6**

0.7 ± 0.4**

0.5 ± 0.4**

0.62

  CD (cm)

0.5 ± 0.2**

0.5 ± 0.3**

0.5 ± 0.3**

0.74

Tethering area (cm ² )

0.8 ± 0.5*

0.5 ± 0.3*

0.7 ± 0.4*

0.21

  MIA (°)

62 ± 9*

43 ± 10^a,c,**

69 ± 4

<0.01

  α1 (°)

55 ± 11

40 ± 9^a,c,*

67 ± 15*

<0.01

  α2 (°)

101 ± 11*

107 ± 16*

85 ± 12^a,b

0.013

  L1 (cm)

1.4 ± 0.3*

1.1 ± 0.1^a,*

1.3 ± 0.1*

0.017