Table 4 Predictors of a lower overall long-term survival by univariate and multivariate Cox proportional hazard regression analysis
Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
Variable | HR | 95% CI | P value | HR | 95% CI | P value |
Age, y | 1.07 | (1.02-1.11) | 0.003 | − | − | − |
Logistic EuroSCORE, % | 1.07 | (1.04-1.09) | <0.001 | 1.06 | (1.03-1.09) | <0.001a |
EuroSCORE II, % | 1.07 | (1.04-1.10) | <0.001 | 1.06 | (1.02-1.09) | 0.002b |
Logistic EuroSCORE ≥40% | 14.28 | (5.65-36.11) | <0.001 | 16.69 | (4.23-65.84) | <0.001c |
EuroSCORE II ≥25% | 6.16 | (2.81-13.48) | <0.001 | 4.31 | (1.67-11.14) | 0.003d |
Preoperative LVEF <30% | 4.31 | (1.58-11.81) | 0.004 | − | − | − |
PAP (systolic), mmHg | 1.03 | (1.00-1.06) | 0.069 | − | − | − |
PAP (diastolic), mmHg | 1.04 | (1.00-1.08) | 0.071 | − | − | − |
Mean PAP, mmHg | 1.04 | (1.00-1.08) | 0.059 | − | − | − |
Preoperative inotropic drug support | 3.51 | (1.56-7.90) | 0.002 | 6.27 | (1.97-19.95) | 0.002e |
Preoperative IABP requirement | 2.69 | (1.25-5.77) | 0.011 | − | − | − |
Serum creatinine, μmol/L | 1.00 | (1.00-1.01) | 0.059 | − | − | − |
Acute renal failure | 2.29 | (0.96-5.48) | 0.062 | − | − | − |
Cardiogenic shock | 3.37 | (1.35-8.41) | 0.009 | − | − | − |
Salvage/Emergent mitral valve surgery | 2.56 | (1.08-6.06) | 0.032 | − | − | − |
MVR without preservation of the subvalvular apparatus | 2.60 | (1.23-5.46) | 0.012 | 3.40 | (1.19-9.69) | 0.022e |
No concomitant CABG | 1.89 | (0.89-4.01) | 0.098 | − | − | − |
Concomitant septal rupture | 4.17 | (0.94-18.54) | 0.061 | − | − | − |
Cardiopulmonary bypass time, min | 1.01 | (1.00-1.01) | 0.026 | − | − | − |
Intraoperative IABP requirement | 2.99 | (1.37-6.51) | 0.006 | − | − | − |