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Table 4 Predictors of a lower overall long-term survival by univariate and multivariate Cox proportional hazard regression analysis

From: Long-term survival after mitral valve surgery for post-myocardial infarction papillary muscle rupture

  Univariate analysis Multivariate analysis
Variable HR 95% CI P value HR 95% CI P value
Age, y 1.07 (1.02-1.11) 0.003
Logistic EuroSCORE, % 1.07 (1.04-1.09) <0.001 1.06 (1.03-1.09) <0.001a
EuroSCORE II, % 1.07 (1.04-1.10) <0.001 1.06 (1.02-1.09) 0.002b
Logistic EuroSCORE ≥40% 14.28 (5.65-36.11) <0.001 16.69 (4.23-65.84) <0.001c
EuroSCORE II ≥25% 6.16 (2.81-13.48) <0.001 4.31 (1.67-11.14) 0.003d
Preoperative LVEF <30% 4.31 (1.58-11.81) 0.004
PAP (systolic), mmHg 1.03 (1.00-1.06) 0.069
PAP (diastolic), mmHg 1.04 (1.00-1.08) 0.071
Mean PAP, mmHg 1.04 (1.00-1.08) 0.059
Preoperative inotropic drug support 3.51 (1.56-7.90) 0.002 6.27 (1.97-19.95) 0.002e
Preoperative IABP requirement 2.69 (1.25-5.77) 0.011
Serum creatinine, μmol/L 1.00 (1.00-1.01) 0.059
Acute renal failure 2.29 (0.96-5.48) 0.062
Cardiogenic shock 3.37 (1.35-8.41) 0.009
Salvage/Emergent mitral valve surgery 2.56 (1.08-6.06) 0.032
MVR without preservation of the subvalvular apparatus 2.60 (1.23-5.46) 0.012 3.40 (1.19-9.69) 0.022e
No concomitant CABG 1.89 (0.89-4.01) 0.098
Concomitant septal rupture 4.17 (0.94-18.54) 0.061
Cardiopulmonary bypass time, min 1.01 (1.00-1.01) 0.026
Intraoperative IABP requirement 2.99 (1.37-6.51) 0.006
  1. aModel 1; bModel 2; cModel 3; dModel 4; eModel 5.
  2. CABG = coronary artery bypass grafting; CI = confidence interval; HR = hazard ratio; IABP = intra-aortic balloon pump; LVEF = left ventricular ejection fraction; MVR = mitral valve replacement; PAP = pulmonary artery pressure.