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Table 1 Comparison between the demographic, clinical and biochemical parameters of the patients with and without intraoperative TXA administration, preoperatively

From: Prophylactic intraoperative tranexamic acid administration and postoperative blood loss after transapical aortic valve implantation

 

Total

TXA-group

Non-TXA-group

P

(n = 146)

(n = 54)

(n = 92)

Female sex (n) %

(90) 62

(28) 51

(62) 67

0.07

Age (years)

81.5 ± 6.6

81.4 ± 6.2

81.7 ± 6.8

0.12

BMI (kg/m 2 )

27.0 ± 4.4

27.2 ± 3.7

26.9 ± 4.4

0.821

Logistic ES (%)

28.7 ± 18.8

27.4 ± 19.5

29.3 ± 18.6

0.606

STS score (%)

12.1 ± 5.0

12.1 ± 5.2

12.1 ± 4.9

0.989

Ejection fraction (%)

54.7 ± 15.7

55.2 ± 17.1

55.5 ± 14.3

0.402

Diabetes mellitus, (n) %

(49) 34

(15) 28

(45) 49

0.110

CAD (n) %

(84) 59

(32) 59

(52) 56

0.540

COPD (n) %

(42) 29

(15) 28

(27) 29

0.936

Previous heart surgery (n) %

(36) 25

(14) 26

(22) 24

0.549

Aspirin (n) %

(82) 56

(25) 46

(57) 62

0.213

Pre-op serum Crea (mg/dL)

1.2 ± 0.5

1.3 ± 0.5

1.1 ± 0.5

0.074

Platelet count (10 3 /mm 3 )

243.7 ± 43.5

238.4 ± 80.9

250.1 ± 56.6

0.336

Pre-op Hb (g/dL)

12.3 ± 1.6

12.5 ± 1.6

12.2 ± 1.6

0.398

Pre-op Hct (%)

37.0 ± 5.1

37.4 ± 4.6

37.1 ± 4.2

0.778

PTT

27.5 ± 7.4

27.5 ± 4.4

28.0 ± 8.2

0.296

Quick

96.4 ± 18.6

94.8 ± 20.1

97.6 ± 18.9

0.304

  1. BMI: body mass index, CAD: coronary artery disease; COPD,: chronic obstructive pulmonary disease, Hb: hemoglobin, Hct: hematocrit, ICU: intensive care unit; NYHA: New York Heart Association, PTT: partial thromboplastin time, STS: Society of Thoracic Surgeons, TXA, tranexamic acid.