Table 2 Comparison of perioperative characteristics of mortality and survival amongst hyperlactatemic patients
Non-survivors (n = 17) | Survivors (n = 127) | p-value | |
|---|---|---|---|
Pre-operative characteristics | |||
Gender (male) | 9 (52.9 %) | 84 (66.1 %) | 0.29 |
Age (years) | 75 (56–87) | 70 (43–89) | 0.12 |
Parsonnet score | 31.5 (17.0–49.0) | 16.8 (0–46.5) | <0.0001 |
Parsonnet score greater than 31 | 20 (15.8 %) | 9 (52.9 %) | 0.001 |
Operation status (emergency) | 3 (17.7 %) | 14 (11.5 %) | 0.03 |
Surgery type | 0.36 | ||
Dialysis | 3 (17.7 %) | 3 (2.4 %) | 0.02 |
Chronic Obstructive Pulmonary Disease | 4 (23.5 %) | 6 (4.7 %) | 0.02 |
Congestive Heart Failure | 11 (64.7 %) | 50 (39.4 %) | 0.05 |
Post-operative characteristics | |||
Cardiopulmonary Bypass time (min) | 153 (83–214) | 110 (25–302) | 0.01 |
Post-operative Intra-aortic Balloon Pump | 8 (47.1 %) | 21 (16.5 %) | 0.003 |
Time to peak lactate >30 h | 11 (64.7 %) | 3 (2.4 %) | <0.0001 |
Time to peak lactate (hours) | 37.6 (1.3–385) | 7.5 (0.25–755.5) | <0.0001 |
Peak arterial lactate (mmol/L) | 10.2 (2.4–18) | 4.4 (1.7–13.1) | 0.0002 |
Total Mechanical Ventilation Days | 3.14 (0–76.5) | 0.89 (0.14–44.1) | 0.0001 |
Acute kidney injury | 16 (100 %) | 64 (51.6 %) | 0.0002 |
Peak creatinine (μmol/L) | 309 (107–738) | 119 (66–840) | <0.0001 |
Postoperative rise in creatinine (%) | 30 (−80 to 254) | 164 (31 to 660) | <0.0001 |