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Table 1 Effects of multiple variables on the MACCE in Cox Regression analysis

From: Red blood cell distribution width predicts long term cardiovascular event after on-pump beating coronary artery bypass grafting

 

Univariate Analysis

Multivariate Analysis

Characteristics

HR

95 % CI

P

HR

95 % CI

P

Age (years)

1.063

1.026–1.102

0.001*

1.024

0.974–1.076

0.36

Male Sex

1.038

0.491–2.192

0.92

   

Obesity

1.444

0.701–2.977

0.31

   

CrCL

0.99

0.978–1.001

0.08

   

hs-CRP

1.003

0.994–1.013

0.51

   

RDW

1.175

1.044–1.322

0.007*

1.227

1.052–1.430

0.009*

Hg

0.755

0.472–1.209

0.24

   

EuroSCORE II

1.099

1.043–1.159

<0.001*

1.069

0.955–1.1197

0.24

USAP

0.941

0.457–1.937

0.87

   

History of MI (>21 days)

1.952

1.017–3.749

0.044*

2.135

0.934–4.883

0.07

History of PCI-CABG

0.496

0.123–2.007

0.32

   

Current smoker

0.630

0.322–1.232

0.17

   

Family history of CAD

0.399

0.175–0.905

0.028*

0.450

0.185–1.091

0.07

Diabetes mellitus

1.155

0.591–2.259

0.67

   

Hyperlipidemia

0.928

0.451–1.911

0.84

   

Hypertension

2.391

1.206–4.738

0.013*

2.064

0.967–4.404

0.06

COPD

1.630

0.578–4.594

0.35

   

Asymtomatic Carotid Stenosis

2.206

1.101–4.420

0.026*

1.353

0.579–3.159

0.48

PVD

0.947

0.242–3.708

0.93

   

History of Stroke

1.131

0.155–8.260

0.90

   

LMCA stenosis

1.957

0.896–4.272

0.09

   

Average number of vessel disease

2.238

1.081–4.633

0.030*

1.275

0.162–10.031

0.81

Three vessel disease

2.728

1.141–6.524

0.024*

1.664

0.126–22.034

0.69

Severe left ventricular dysfunction

1.481

0.455–4.821

0.51

   

Mitral insufficiency

1.873

0.824–4.253

0.13

   

Number of distal anastomosis

1.396

0.998–1.953

0.05

   

Endarterectomy per anastomosis

1.358

0.715–2.577

0.35

   

Duration of hospital stay

1.143

1.072–1.218

<0.001*

1.070

0.935–1.224

0.32

Prolonged respiratory period

3.673

2.109–6.398

<0.001*

2.417

0.466–12.551

0.29

Duration of ICU stay

1.020

1.009–1.032

<0.001*

1.002

0.969–1.035

0.92

Perioperative AF

2.026

0.926–4.421

0.07

   

Perioperative MI

0.993

0.352–2.804

0.99

   

Pulmonary Complication

1.451

0.793–2.655

0.22

   

Perioperative Renal Failure

1.880

0.890–3.973

0.09

   

Cerebrovascular Complication

1.465

0.519–4.130

0.47

   

Mean number of blood unit

1.204

1.008–1.438

0.041*

0.851

0.618–1.197

0.24

Rehospitalization

1.789

1.014–3.157

0.045*

1.823

0.925–3.592

0.08

  1. *Statistically significant difference. Values are presented as mean ± standard deviation or number (%), where appropriate. AF atrial fibrillation, CAD coronary artery disease, CI confidence interval, COPD chronic obstructive pulmonary disease, CrCL creatinin clearance, hs-CRP high sensitive C-reactive protein, EuroSCORE II European System for Cardiac Operative Risk Evaluation, Hg haemoglobin level, HR hazard ration, ICU intensive care unit, LMCA left main coronary artery, MACCE major cardiac and cerebrovascular event, MI myocardial infarction, MPV mean platelet volume, OR odds ratio, PCI percutaneous coronary intervention, PVD peripheral vascular disease, RDW red blood cell distribution width, USAP unstabil angina pectoris