Smooth muscle cell sheet transplantation preserve cardiac function and minimize cardiac remodeling in a rat myocardial infarction model

Table 1 Ventricular morphology and fibrosis

Group	LV volume (mm³)	Scar area (mm²)	Scar thickness (mm)	PW thickness (mm)	Fibrosis (%)
Sham	335.1 ± 16.5	–	–	1.87 ± 0.09	1.26 ± 0.16
SMC-Tx	402.9 ± 5.5*	49.4 ± 2.3	1.09 ± 0.05	1.85 ± 0.04	0.87 ± 0.18
DFB-Tx	497.0 ± 24.2^,*	83.1 ± 7.4**	0.89 ± 0.05**	1.57 ± 0.06^,*	2.33 ± 0.26^,*
Untreated	489.9 ± 18.7^,*	86.6 ± 11.8**	0.76 ± 0.06**	1.46 ± 0.07^,*	2.22 ± 0.35^,*

Summary of LV morphological data by planimetry and fibrosis of non-infarcted myocardium collected for each group at twenty-eight days after cell sheet transplantation. LV left ventricular, PW posterior wall, SMC-Tx smooth muscle cell sheet transplantation group, DFB-Tx dermal fibroblast sheet transplantation group, Untreated, untreated group. Each groups n = 5.*p<0.05 vs. Sham, **p<0.05 vs. SMC-Tx.

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