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Table 1 Treatment Courses of the 6 Patients Receiving HTx for primary cardiac sarcomas in Our Institution

From: Survival after heart transplantation for non-metastatic primary cardiac sarcoma

Age/Sex

Histology (Grade)

Tumor Sites

Operations before HTX, Interval (mo)

Multimodal Therapies

Tumor Relapse (mo)

Outcome Survival (mo)

63/M

Synovial Sarcoma (G3)

LV, RV

Partial resection, 7

NT(pre-), XRT to metastasis

Lung (1)

D, 5

48/M

Angiosarcoma (G3)

RA, RV

Biopsy, 3

IAP(post-op)

Liver, Chest (4),

D, 5

27/F

Angiosarcoma (G3)

RA, RV

Biopsy, 2

IAP(post-op)

Lung (12)

D, 15

49/F

Undifferentiated Pleomorphic Sarcoma (G3)

RA, LA, LV

Partial resection, 5

Re-HTx at 36mo

PV (33), Liver, PV (40)

D, 43

49/F

Undifferentiated Pleomorphic Sarcoma (G2)

LA, LV

Partial resection, 9

No

-

Da, 18

61/M

Myxoid Liposarcoma, (G2)

RV

Partial resection, 3

No

-

Alive, 93

  1. aComplicated by one episode of acute rejection, heart failure unrelated to tumor was the reason of death
  2. D death, F female, HT, heart transplantation, IAP ifosfamide/doxorubicin/cisplatin, LA left atrium, LV left ventricular, M male, NT vinorelbine/cisplatin, RA right atrium, RV right ventricular, XRT radiation therapy