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Table 1 Baseline characteristics of patients of the Prior Coronary Artery Bypass Graft Surgery and the Initial Transapical Transcatheter Aortic Valve Replacement Groups

From: Transapical transcatheter aortic valve replacement in patients with or without prior coronary artery bypass graft operation

 

No CABG (N = 81)

CABG (N = 45)

P Value

Age

85.8 ± 6.1

82.5 ± 7.4

0.008

Male, (%)

24 (29.6)

28 (62.2)

<0.001

BMI

25.58 ± 4.84

25.41 ± 4.70

0.853

STS Score

8.99 ± 4.19

11.66 ± 5.47

0.003

NYHA III or IV

56 (69.1)

34 (75.6)

0.539

Permanent PM

9 (11.1)

10 (22.2)

0.120

ICD

3 (3.7)

8 (17.8)

0.017

Atrial Fibrillation

27 (33.3)

20 (44.4)

0.251

Previous MI

16 (21.1)

22 (55)

<0.001

Prior PCI

41 (50.6)

20 (44.4)

0.578

Stroke

8 (9.9)

7 (15.6)

0.395

Transient Ischemic Attack

6 (7.4)

6 (13.3)

0.346

PAD

25 (30.9)

20 (44.4)

0.174

Smoking History

52 (64.2)

30 (66.7)

0.847

Hypertension

69 (85.2)

42 (93.3)

0.253

Dyslipidemia

59 (72.8)

40 (88.9)

0.042

Diabetes

19 (23.5)

20 (44.4)

0.017

Oral Medications only

9 (11.1)

11 (24.4)

0.073

Insulin only

5 (6.2)

5 (11.1)

0.328

Immunocompromise Present

12 (14.8)

1 (2.2)

0.031

Left Main Stenosis > 50%

4 (4.9)

19 (42.2)

<0.001

Proximal LAD > 70% stenosis

13 (16.0)

26 (57.8)

<0.001

Renal Dialysis

3 (3.7)

1 (2.2)

1.0

Creatinine mg/dl

1.28 ± 0.65

1.32 ± 0.48

0.686

Echocardiography

   

 Aortic Valve Area, cm2

0.67 ± 0.14

0.75 ± 0.20

0.025

 LVEF (%)

54.3 ± 11.6

42.3 ± 15.3

<0.001

 Aortic Valve Mean Gradient, mm Hg

47.7 ± 12.5

44.1 ± 11.9

0.126

 Aortic Valve Peak Gradient, mm Hg

82.5 ± 22.4

75.8 ± 18.6

0.091

 Aortic Valve Regurgitation Moderate/Severe

1 (1.2)

1 (2.2)

1.0

 Mitral Valve Regurgitation Moderate/Severe

13 (16.0)

16 (35.6)

0.016

 LVIDs, cm

3.42 ± 1.21

4.05 ± 1.88

0.026

 LVIDd, cm

4.96 ± 1.14

5.30 ± 1.91

0.212

  1. Results are number (%) or mean ± standard deviation
  2. CABG Coronary artery bypass graft, BMI Body mass index, NYHA New York Heart Association classification, STS Society of Thoracic Surgeons, PM Pacemaker, ICD Implantable cardioverter defibrillator, MI Myocardial infarction, PCI Percutaneous coronary intervention, PAD Peripheral arterial disease, LAD Left anterior descending, LVEF Left ventricular ejection fraction, LVIDs Left ventricular diameter at end systole, LVIDd Left ventricular diameter at end diastole