Fig. 3From: Tissue-engineered cardiac patch seeded with human induced pluripotent stem cell derived cardiomyocytes promoted the regeneration of host cardiomyocytes in a rat modelHistological analysis of the grafts at 4, 8 and, 16 weeks after implantation. Hematoxylin and Eosin (H&E) staining demonstrated dense cellular infiltration into the hiPS-CMs seeded or unseeded cardiac patches (a - f: high magnification images, g - l: low magnification images). Both seeded and unseeded patches explants did not stain positive for α-actinin (green) at the 4 and 8 week time point (m, n, p, q). However, there were small islands of cells which stained positive for α-actinin (green) in the cardiac patch 16 weeks after implantation (o, r, s). N native heart muscle, P patchBack to article page