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Table 3 Baseline characteristics and results of univariable analyses

From: Postoperative air leak grading is useful to predict prolonged air leak after pulmonary lobectomy

Variables

No. of cases (%)

P valuea

All

PAL (−)

PAL (+)

(N = 720)

(N = 585)

(N = 135)

Ageb (years)

64 (7–85)

64 (7–85)

66 (14–82)

<0.001c

Male

464 (64.4%)

354 (60.5%)

110 (81.5%)

<0.001

Preoperative medication

 Aspirin or NSAIDs

98 (13.6%)

80 (13.7%)

18 (13.3%)

0.92

 Steroid (including inhalator)

15 (2.1%)

9 (1.5%)

6 (4.4%)

0.05d

Neoadjuvant chemotherapy

50 (6.9%)

39 (6.7%)

11 (8.1%)

0.54

Preoperative spirometry

 FEV1/FVC < 70%

259 (36.0%)

201 (34.4%)

58 (43.0%)

0.04

 FVC% < 80

76 (10.6%)

62 (10.6%)

14 (10.4%)

0.90

 FEV1% < 80

108 (15.0%)

81 (13.8%)

27 (20.0%)

0.04

DLCO% < 80

103 (14.3%)

81 (13.8%)

22 (16.3%)

0.34

Underlying DM

101 (14.0%)

83 (14.2%)

18 (13.3%)

0.80

Preoperative Hb < 10 g/dL

29 (4.0%)

23 (3.9%)

6 (4.4%)

0.41d

Preoperative albumin < 3.0 g/dL

12 (1.7%)

10 (1.7%)

2 (1.5%)

0.32d

BMI < 25.5 kg/m2

523 (72.6%)

416 (71.1%)

107 (79.3%)

0.07

Open thoracotomy

375 (52.1%)

299 (51.1%)

76 (56.3%)

0.28

Right side operation

456 (63.3%)

352 (60.2%)

104 (77.0%)

<0.001

Upper lobectomy

372 (51.7%)

293 (50.1%)

79 (58.5%)

0.08

Combined chest wall resection

21 (2.9%)

17 (2.9%)

4 (3.0%)

1.00d

Pleural adhesion (+)

338 (46.9%)

256 (43.8%)

82 (60.7%)

<0.001

Incomplete fissure (+)

362 (50.3%)

284 (48.5%)

78 (57.8%)

0.05

  1. NSAID denotes non-steroidal anti-inflammatory drug, DM diabetes mellitus, Hb hemoglobin, BMI body mass index. In spirometry variables, FEV 1 denotes forced expiratory volume in one second, FVC forced vital capacity, D L CO diffusing capacity of the lung for carbon monoxide. Suffix ‘%’ means ‘% of predicted normal’
  2. a P values are for comparison between PAL (−) and PAL (+)
  3. bExceptionally, ages are expressed as ‘median (range)’
  4. cMann-Whitney U-test was performed
  5. dFisher’s exact test was performed. In other cases, χ2 test was performed