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Table 2 Morbidity and mortality in patients stratified by smoking status

From: Smoking and timing of cessation on postoperative pulmonary complications after curative-intent lung cancer surgery

  

Current smokers

Ex-smokers

<6 weeks

Ex-smokers

≥6 weeks

Never smokers

p-value

  

(n = 111)

(n = 55)

(n = 245)

(n = 51)

 

PPC Frequency

21.6% (n = 24)d

10.9% (n = 6)c,d

11.8% (n = 29)c,d

2.0% (n = 1)c

0.004a

ITU admission

14.4% (n = 16)d

5.5% (n = 3)c,d

4.5% (n = 11)c,d

0%c

0.001b

Median (IQR) LOS (days)

6 (5)d

5 (3)c,d

6 (4)c,d

5 (2)c

0.001f

Median (IQR) ITU LOS (days)

4 (10) (n = 16)e

2 ( * ) (n = 3)c,d,e

3 (2) (n = 11)c,d

0 (0) (n = 0)c

0.002f

30-day hospital readmissions

13.6% (n = 15)

14.8% (n = 8)

15.1% (n = 36)

7.8% (n = 4)

0.793a

Mortality

Total

30.6% (n = 34)

32.7% (n = 18)

30.2% (n = 74)

23.5% (n = 12)

0.744a

30-day

1.8% (n = 2)

0%

2.4% (n = 6)

2.0% (n = 1)

0.874b

90-day

5.4% (n = 6)

1.8% (n = 1)

3.2% (n = 8)

5.9% (n = 3)

0.575b

Cause of death

Early Postoperative Complications

2.7% (n = 3)

3.6% (n = 2)

2.9% (n = 7)

2.0% (n = 1)

0.970b

Cancer related

18.9% (n = 21)

20.0% (n = 11)

20.4% (n = 50)

17.6% (n = 9)

0.968a

Non-cancer related

6.3% (n = 7)

5.5% (n = 3)

6.9% (n = 17)

1.9% (n = 1)

0.768b

Uncertain

2.7% (n = 3)

3.6% (n = 2)

0%

1.9% (n = 1)

0.015b

Mean (95%CI) overall survival (months) excluding early postoperative complications

42 (42–45)

42 (38–47)

43 (40–46)

46 (41–50)

0.778g

  1. PPC postoperative pulmonary complication, ITU intensive therapy unit, LOS length of stay.a Chi-square test with Bonferroni post-hoc analysis;b Fisher’s Exact test with Bonferroni post-hoc analysis. When overall p-value is less than 0.05; each subscript letter(c-e) denotes a subset of smoking category whose column proportion does not differ significantly from each other (Bonferroni post-hoc multiple comparison test);f kruskal-Wallis test with Dunn-Bonferroni post-hoc multiple comparison test;g ANOVA with Bonferroni post-hoc analysis.;h interquartile range not applicable due to number of patients