Identification of preoperative prediction factors of tumor subtypes for patients with solitary ground-glass opacity pulmonary nodules

Table 2 Correlation between histological subtypes and clinical and CT imaging characteristics

Variable	AIS/MIA(124)	IA(269)	p value
Gender			0.984
Male	37	80
Female	87	189
Median age	55.85 ± 9.42	58.49 ± 9.00	0.008*
Smoking			0.246
Current/ever	98	198
Never	26	71
History of family cancer			0.046*
Yes	45	71
No	79	198
CEA	1.5 (1.0,2.4)	2.1 (1.3,3.1)	0.000*
CA19–9	11.0 (8.4,17.4)	9.4 (6.5,15.3)	0.081
Location of tumor			0.084
RUL	52	111
RML	8	12
RLL	15	50
LUL	39	59
LLL	10	37
GGO size	1.2 (0.8,1.6)	2.0 (1.6,2.5)	0.000*
GGO type			0.000*
pGGO	90	77
mGGO	34	192
Air bronchogram	18	71	0.074
Bubble-like sign	22	92	0.001*
Spicule sign	32	79	0.140
Pleural tag	31	71	0.163
Pathological stage			0.000*
0/IA	124	255
IB	0	14
Lymphatic metastasis	–	–	–

^*Statistically significant p value, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9, pGGO pure ground-glass opacity nodule, mGGN mixed ground-glass opacity nodule, RUL superior lobe of right lung, RML middle lobe of right lung, RLL inferior lobe of right lung, LUL superior lobe of left lung, LLL inferior lobe of left lung

ISSN: 1749-8090