Table 3 Definition criteria for perioperative myocardial ischemia after coronary artery bypass grafting

Rasmussen

1997

One or more of the following criteria:

- new changes in the ST-segment in the ECG;

- new Q-waves in the ECG;

- CK-MB >80 U/L;

- recurrent episodes of, or sustained ventricular tachyarrhythmia;

- ventricular fibrillation;

- hemodynamic deterioration and left ventricular failure.

Fabricius

2001

One or more of the following criteria:

- increase in CK/CK-MB above 10%;

- ischemic electrocardiographic episodes (new changes in ST-segment lasting at least 1 min and involving a shift from baseline of greater than or equal to 0.1 mV of ST-depression and a new postoperative Q;

- recurrent episodes of, or sustained ventricular tachyarrhythmia or ventricular fibrillation;

- hemodynamic deterioration despite adequate inotropic support.

Thielmann

2006

One or more of the following criteria:

- cTnI serum level >20 ng/ml within 24 h after surgery;

- ST-segment deviations at the J point in two or more contiguous leads with cut-off points ≥0.2 mV in leads V1, V2, or V3 and 0.1 mV in other leads or T-wave abnormalities in two or more contiguous leads as previously described;

- hemodynamic instability despite intravenous inotropic support (>0.3 mg/kg/min).

Karhunen

2010

One or more of the following criteria:

- ST-level changes in ECG and increased levels of cardiac biomarkers, creatine phosphokinase isoenzyme CK-MB or Tn;

- ECG changes or findings of poor myocardial function or a new wall motion abnormality in echocardiography.

Laflamme

2012

One or more of the following criteria:

- ECG modifications (new ST segment alterations or new Q wave);

- refractory malignant arrhythmias;

- elevation of cardiac biomarkers;

- persistent low cardiac output syndrome;

- new echocardiography wall motion abnormalities.

Szavits-Nossan

2012

One or more of the following criteria:

- hemodynamical deterioration;

- new ST segment depression or elevation greater than 1 mm;

- isoenzyme ratio of creatinine phosphokinase > 0.1;

- cardiac troponin >0.1 mmol/L;

- sustained ventricular tachycardia;

- repeated nonsustained ventricular tachycardia and ventricular fibrillation.

Davierwala

2013

One or more of the following criteria:

- electrocardiographic alterations;

- CK-MB >2x normal;

- new regional wall motion abnormalities on echocardiography;

- repetitive ventricular arrhythmias;

- hemodynamic instability.

Hultgren

2016

One or more of the following criteria:

- ECG changes;

- chest pain;

- Aspartate aminotransferase (ASAT) on postoperative day 1 >2.5 μkat/l;

- Troponin T measured 3-4 days after surgery > 2000 ng/L.

Preußer

2017

One or more of the following criteria:

- progressive postoperative elevation of cardiac enzymes;

- ECG changes suggestive of myocardial ischemia (such as ST segment alteration);

- major ventricular arrhythmia of unclear cause.