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Table 3 Definition criteria for perioperative myocardial ischemia after coronary artery bypass grafting

From: Control angiography for perioperative myocardial Ischemia after coronary surgery: meta-analysis

Authors Year of publication Definition criteria
Rasmussen 1997 One or more of the following criteria:
- new changes in the ST-segment in the ECG;
- new Q-waves in the ECG;
- CK-MB >80 U/L;
- recurrent episodes of, or sustained ventricular tachyarrhythmia;
- ventricular fibrillation;
- hemodynamic deterioration and left ventricular failure.
Fabricius 2001 One or more of the following criteria:
- increase in CK/CK-MB above 10%;
- ischemic electrocardiographic episodes (new changes in ST-segment lasting at least 1 min and involving a shift from baseline of greater than or equal to 0.1 mV of ST-depression and a new postoperative Q;
- recurrent episodes of, or sustained ventricular tachyarrhythmia or ventricular fibrillation;
- hemodynamic deterioration despite adequate inotropic support.
Thielmann 2006 One or more of the following criteria:
- cTnI serum level >20 ng/ml within 24 h after surgery;
- ST-segment deviations at the J point in two or more contiguous leads with cut-off points ≥0.2 mV in leads V1, V2, or V3 and 0.1 mV in other leads or T-wave abnormalities in two or more contiguous leads as previously described;
- hemodynamic instability despite intravenous inotropic support (>0.3 mg/kg/min).
Karhunen 2010 One or more of the following criteria:
- ST-level changes in ECG and increased levels of cardiac biomarkers, creatine phosphokinase isoenzyme CK-MB or Tn;
- ECG changes or findings of poor myocardial function or a new wall motion abnormality in echocardiography.
Laflamme 2012 One or more of the following criteria:
- ECG modifications (new ST segment alterations or new Q wave);
- refractory malignant arrhythmias;
- elevation of cardiac biomarkers;
- persistent low cardiac output syndrome;
- new echocardiography wall motion abnormalities.
Szavits-Nossan 2012 One or more of the following criteria:
- hemodynamical deterioration;
- new ST segment depression or elevation greater than 1 mm;
- isoenzyme ratio of creatinine phosphokinase > 0.1;
- cardiac troponin >0.1 mmol/L;
- sustained ventricular tachycardia;
- repeated nonsustained ventricular tachycardia and ventricular fibrillation.
Davierwala 2013 One or more of the following criteria:
- electrocardiographic alterations;
- CK-MB >2x normal;
- new regional wall motion abnormalities on echocardiography;
- repetitive ventricular arrhythmias;
- hemodynamic instability.
Hultgren 2016 One or more of the following criteria:
- ECG changes;
- chest pain;
- Aspartate aminotransferase (ASAT) on postoperative day 1 >2.5 μkat/l;
- Troponin T measured 3-4 days after surgery > 2000 ng/L.
Preußer 2017 One or more of the following criteria:
- progressive postoperative elevation of cardiac enzymes;
- ECG changes suggestive of myocardial ischemia (such as ST segment alteration);
- major ventricular arrhythmia of unclear cause.
  1. ECG electrocardiogram, CK-MB creatine kinase-MB, Tn troponin