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Table 1 Patient demographics

From: Candidate plasma biomarkers for predicting ascending aortic aneurysm in bicuspid aortic valve disease

Demographic

Non-aneurysmal (n = 7)

Aneurysmal (n = 8)

p-value

Mean age (years)

59.3 ± 13.3

51.8 ± 10.4

0.24

Gender (n)

  

0.32

 Male

3

2

 

 Female

4

6

 

Mean body mass index (kg/m2)

29.9 ± 5.0

29.7 ± 5.1

0.92

Mean maximum ascending aortic diameter (mm)

40.6 ± 2.6

53.4 ± 5

< 0.001

Mean blood pressure (mmHg)

 Systolic

137 ± 15.6

133 ± 16.3

0.61

 Diastolic

73 ± 10.4

76 ± 11.1

0.57

Smoking status (n)

  

0.35

 Non-smoker

5

3

 

 Ex-smoker

2

4

 

 Current smoker

0

1

 

Type 2 diabetes (n)

2

1

0.57

Medications (n patients taking)

 ACE inhibitor

2

1

0.57

 β-blocker

3

2

0.61

 Angiotensin Receptor Blocker

1

0

0.47

 Calcium Channel Blocker

1

0

0.47

 Statin

4

0

0.03

Aortic valve disease (n)

0.33

 Normal

0

0

 

 Stenosis

3

1

 

  Mild

0

0

 

  Mod

0

0

 

  Severe

5

6

 

 Regurgitation

2

2

 

  Mild

1

3

 

  Mod

1

1

 

  Severe

2

3

 

 Mixed

2

5

 

Left ventricular ejection fraction (n)

  

0.47

 45–70%

7

6

 

 35–44%

0

0

 

  < 35%

0

0

 

 Unknown

0

2

 

Mean preoperative blood results

 Haemoglobin (g/dl)

138 ± 15

155 ± 15

0.047

 White cell count (× 109/l)

6.9 ± 1.8

8.7 ± 2.9

0.17

 Platelet count (×109/l)

226 ± 38

235 ± 38

0.65

 Urea (mmol/l)

5.1 ± 1.6

4.7 ± 1.1

0.58

 Creatinine (μmol/l)

85 ± 28

76 ± 23

0.50

 C-reactive protein (CRP; mg/l)

4.0 ± 2.2

4.9 ± 4.1

0.71

 Serum cholesterol (mmol/L)

5.4 ± 0.9

5.3 ± 0.5

0.84

  1. Mean values are given ± standard deviation. P-values are given for independent samples t-tests between the study groups. Significant p-values (p < 0.05) are highlighted in bold