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Table 1 Patient demographics

From: Candidate plasma biomarkers for predicting ascending aortic aneurysm in bicuspid aortic valve disease

Demographic Non-aneurysmal (n = 7) Aneurysmal (n = 8) p-value
Mean age (years) 59.3 ± 13.3 51.8 ± 10.4 0.24
Gender (n)    0.32
 Male 3 2  
 Female 4 6  
Mean body mass index (kg/m2) 29.9 ± 5.0 29.7 ± 5.1 0.92
Mean maximum ascending aortic diameter (mm) 40.6 ± 2.6 53.4 ± 5 < 0.001
Mean blood pressure (mmHg)
 Systolic 137 ± 15.6 133 ± 16.3 0.61
 Diastolic 73 ± 10.4 76 ± 11.1 0.57
Smoking status (n)    0.35
 Non-smoker 5 3  
 Ex-smoker 2 4  
 Current smoker 0 1  
Type 2 diabetes (n) 2 1 0.57
Medications (n patients taking)
 ACE inhibitor 2 1 0.57
 β-blocker 3 2 0.61
 Angiotensin Receptor Blocker 1 0 0.47
 Calcium Channel Blocker 1 0 0.47
 Statin 4 0 0.03
Aortic valve disease (n) 0.33
 Normal 0 0  
 Stenosis 3 1  
  Mild 0 0  
  Mod 0 0  
  Severe 5 6  
 Regurgitation 2 2  
  Mild 1 3  
  Mod 1 1  
  Severe 2 3  
 Mixed 2 5  
Left ventricular ejection fraction (n)    0.47
 45–70% 7 6  
 35–44% 0 0  
  < 35% 0 0  
 Unknown 0 2  
Mean preoperative blood results
 Haemoglobin (g/dl) 138 ± 15 155 ± 15 0.047
 White cell count (× 109/l) 6.9 ± 1.8 8.7 ± 2.9 0.17
 Platelet count (×109/l) 226 ± 38 235 ± 38 0.65
 Urea (mmol/l) 5.1 ± 1.6 4.7 ± 1.1 0.58
 Creatinine (μmol/l) 85 ± 28 76 ± 23 0.50
 C-reactive protein (CRP; mg/l) 4.0 ± 2.2 4.9 ± 4.1 0.71
 Serum cholesterol (mmol/L) 5.4 ± 0.9 5.3 ± 0.5 0.84
  1. Mean values are given ± standard deviation. P-values are given for independent samples t-tests between the study groups. Significant p-values (p < 0.05) are highlighted in bold