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Table 1 Clinical and utility data used in the model for sNPWT compared to standard care in patients following CABG surgery. The table shows the baseline data, effectiveness of sNPWT and health related quality of life (utility) data that was applied in the model

From: Cost-effectiveness analysis of single use negative pressure wound therapy dressings (sNPWT) compared to standard of care in reducing surgical site complications (SSC) in patients undergoing coronary artery bypass grafting surgery

Outcome Mean Number of patients Events Distribution Reference
Baseline SSC rate 0.048 2621 127 Beta Cristofolini [16]
Mortality with SSC 0.017 118 2 Beta ibid
Mortality without SSC 0.007 2503 18 Beta
Readmission SSC 0.034 118 4 Beta
Readmission No SSC 0.000 2503 1 Beta
Revision SSC 0.068 118 8 Beta
Revision No SSC 0.005 2503 12 Beta
All-cause mortality 0.003     [18]
Multiplier for revision mortality 1.300     Wu [19]
Length of stay data
 Length of stay with surgical site complications Mean Lower CI Upper CI   
 Intensive care unit 15.2 1 87.2 Log normal Cristofolini [16]
 Intermediate care 4.8 0.5 25.2 Log normal
 General ward 22.3 0.5 68.4 Log normal
Length of stay without surgical site complications
 Intensive care unit 3.8 1 26 Log normal Cristofolini [16]
 Intermediate care 2.4 0.5 10 Log normal
 General ward 8.3 0.5 19 Log normal
Utility data used in the model
 Parameter Mean Alpha Beta Distribution Source
 Disutility with SSI 0.2 8 41 Beta Tuffaha [13]
 Utility with no SSI 0.91 185 18 Beta
Effectiveness data (Odds ratio and 95% CI)
 Outcome Mean Lower CI Upper CI Distribution Source
 Odds ratio for SSC 0.220 0.060 0.810 Log normal Witt-Majchrzak [17]
 Reduction in LOS (days) 0.500 0.020 0.70 Log normal Strugala [14]
  1. Abbreviations: sNPWT single use negative pressure wound therapy, SSC surgical site complications, CI confidence interval, LOS length of stay