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Table 1 Low dose inhibitors (Comparison of low dose BTX-A and papaverine)

From: Relaxation matters: comparison of in-vitro vasodilatory role of botulinum toxin-A and papaverine in human radial artery grafts

Vasoconstrictor

Inhibitor agent

0th hour

2nd hour

5-HT 10− 6 M

BTX-A 10− 8 M

87.3 ± 11.1%

80.0 ± 7.1%

Pap 10− 6 M

35.2 ± 10.1% *

51.9 ± 6.3% *

ET-1 10− 8 M

BTX-A 10− 8 M

54.3 ± 12.3%

46.5 ± 10.4%

Pap 10− 6 M

61.0 ± 14.2%

84.2 ± 23.1% *

  1. 5-HT: Serotonin, BTX-A: Botulium toxin A, ET-1: Endothelin 1, Pap: Papaverine. Results are % of vasoconstrictor (5-HT or ET-1) elicited maximal control contractions (Mean ± SD). *p < 0.05 compared to same hour BTX-A 10− 8 M (boldface entries)
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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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