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Table 2 High dose inhibitors (Comparison of high dose BTX-A and papaverine)

From: Relaxation matters: comparison of in-vitro vasodilatory role of botulinum toxin-A and papaverine in human radial artery grafts

Vasoconstrictor Inhibitor agent 0th hour 2nd hour
5-HT 10− 6 M BTX-A 10− 6 M 67.8 ± 7.5% 61.6 ± 6.3%
Pap 10− 4 M 11.3 ± 6.1% * 19.7 ± 6.4% *
ET-1 10− 8 M BTX-A 10− 6 M 46.5 ± 10.7% 44.4 ± 16.8%
Pap 10− 4 M 41.0 ± 13.2% 67.4 ± 23.7%
  1. 5-HT: Serotonin, BTX-A: Botulium toxin A, ET-1: Endothelin 1, Pap: Papaverine. Results are % of vasoconstrictor (5-HT or ET-1) elicited maximal control contractions (Mean ± SD). *p < 0.05 compared to same hour BTX-A 10−6 M (boldface entries)