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Table 2 High dose inhibitors (Comparison of high dose BTX-A and papaverine)

From: Relaxation matters: comparison of in-vitro vasodilatory role of botulinum toxin-A and papaverine in human radial artery grafts

Vasoconstrictor

Inhibitor agent

0th hour

2nd hour

5-HT 10− 6 M

BTX-A 10− 6 M

67.8 ± 7.5%

61.6 ± 6.3%

Pap 10− 4 M

11.3 ± 6.1% *

19.7 ± 6.4% *

ET-1 10− 8 M

BTX-A 10− 6 M

46.5 ± 10.7%

44.4 ± 16.8%

Pap 10− 4 M

41.0 ± 13.2%

67.4 ± 23.7%

  1. 5-HT: Serotonin, BTX-A: Botulium toxin A, ET-1: Endothelin 1, Pap: Papaverine. Results are % of vasoconstrictor (5-HT or ET-1) elicited maximal control contractions (Mean ± SD). *p < 0.05 compared to same hour BTX-A 10−6 M (boldface entries)