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Table 3 Univariate and multivariate Cox proportional hazard regression analysis of the clinicopathological parameters of all patients (n = 231)

From: Solid component tumor doubling time is a prognostic factor in non-small cell lung cancer patients

  Univariate Multivariate
HR 95%CI p-value HR 95%CI p-value
Overall survival
 Age (< 70) 0.628 0.366–1.077 0.091    
 Sex (Female) 0.49 0.368–0.651 < 0.001 0.459 0.177–1.192 0.11
 pStage (II–IV) 3.291 2.061–5.235 < 0.001 2.344 1.4–3.924 0.001
 Smoking history (Yes) 3.85 2.257–6.568 < 0.001 1.346 0.533–3.403 0.53
 Histological type (non-adeno) 3.272 2.078–5.153 < 0.001 1.327 0.776–2.271 0.302
 Solid TDT (< 400 d) 3.034 1.682–5.473 < 0.001 2.093 1.111–3.944 0.022
Recurrence-free survival
 Age (< 70) 1.331 0.786–2.254 0.287    
 Sex (Female) 0.639 0.494–0.827 0.001 0.318 0.128–0.788 0.013
 pStage (II–IV) 4.067 2.537–6.52 0.001 2.846 1.662–4.874 < 0.001
 Smoking history (Yes) 2.161 1.325–3.525 0.002 0.489 0.197–1.211 0.122
 Histological type (non-adeno) 2.897 1.811–4.633 < 0.001 1.617 0.894–2.922 0.112
 Solid TDT (< 400 d) 3.152 1.673–5.939 < 0.001 2.099 1.063–4.144 0.033
  1. HR Hazrad Ratio, 95% CI 95% Confidence Interval