Table 1 Baseline clinicopathologic characteristics of 163 patients
Variables | All patients | Subcarinal node (−) | Subcarinal node (+) | p value |
|---|---|---|---|---|
n = 163 (%) | n = 89 | n = 74 | ||
Age at surgery | ||||
< 60 years | 89 (54.6%) | 49 | 40 | 0.898 |
≥ 60 years | 74 (45.4%) | 40 | 34 | |
Gender | ||||
Male | 132 (81.0%) | 74 | 58 | 0.440 |
Female | 31 (19.0%) | 15 | 16 | |
Smoking status | ||||
Smoker | 121 (74.2%) | 67 | 54 | 0.737 |
Never-smoker | 42 (25.8%) | 22 | 20 | |
PET scan | ||||
Yes | 63 (38.7%) | 34 | 29 | 0.897 |
No | 100 (61.3%) | 55 | 45 | |
Preopeative biopsy | ||||
SCLC | 40 (24.5%) | 20 | 20 | 0.793 |
Other types of cancer | 37 (22.7%) | 20 | 17 | |
Cancer not diagnosed | 86 (52.8%) | 49 | 37 | |
Surgery type | ||||
Lobectomy | 133 (81.6%) | 72 | 61 | 0.801 |
Pneumonectomy | 30 (18.4%) | 17 | 13 | |
Histology | ||||
Pure SCLC | 117 (71.8%) | 67 | 50 | 0.276 |
Combined SCLC | 46 (28.2%) | 22 | 24 | |
Tumor location | ||||
Upper lobe | 84 (51.5%) | 66 | 18 | < 0.05 |
Middle lobe | 12 (7.4%) | 2 | 10 | |
Lower lobe | 67 (41.1%) | 21 | 46 | |
Tumor endoscopy | ||||
Peripheral | 66 (40.5%) | 37 | 29 | 0.758 |
Central | 97 (59.5%) | 52 | 45 | |
Visceral pleura invasion | ||||
Yes | 23 (14.1%) | 12 | 11 | 0.801 |
No | 140 (85.9%) | 77 | 63 | |
LVI | ||||
Yes | 44 (27.0%) | 23 | 21 | 0.717 |
No | 119 (73.0%) | 66 | 53 | |
Tumor size (cm) | / | 3.69 ± 1.36 | 4.54 ± 1.81 | 0.001 |
≤ 3 | 51 (31.3%) | 34 | 17 | 0.005 |
> 3, ≤ 5 | 77 (47.2%) | 44 | 33 | |
> 5 | 35 (21.5%) | 11 | 24 | |
Cycles of Chemotherapy | ||||
≤ 4 | 96 (58.9%) | 50 | 46 | 0.440 |
> 4 | 67 (41.1%) | 39 | 28 | |
PCI | ||||
Yes | 55 (33.7%) | 33 | 22 | 0.323 |
No | 108 (66.3%) | 56 | 52 | |
PORT to the lung | ||||
Yes | 111 (68.1%) | 65 | 46 | 0.138 |
No | 52 (31.9%) | 24 | 28 | |
Node levels | ||||
Single-station N2 | 85 (52.1%) | 59 | 26 | < 0.05 |
Multiple-station N2 | 78 (47.9%) | 30 | 48 | |
Node-spreading patterns | ||||
Nonskip N2 | 137 (84.0%) | 71 | 66 | 0.102 |
Skip N2 | 26 (16.0%) | 18 | 8 | |