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Table 2 Univariate analysis for overall survival

From: Prediction of lymph node status in completely resected IIIa/N2 small cell lung cancer: importance of subcarinal station metastases

Variables

Univariate Analysis

HR(95% CI)

p value

Age

 < 60 years

1

0.703

 ≥ 60 years

1.07 (0.73–1.57)

 

Gender

 Male

1

0.790

 Female

1.06 (0.65–1.74)

 

Smoking status

 Smoker

1

0.690

 Never-smoker

0.91 (0.59–1.40)

 

PET scan

 Yes

1

0.681

 No

1.08 (0.73–1.59)

 

Histology

 Pure SCLC

1

0.486

 Combined SCLC

1.16 (0.75–1.79)

 

Tumor endoscopy

 Peripheral

1

0.005

 Central

1.83 (1.20–2.78)

 

Visceral pleura invasion

 Yes

1

0.624

 No

0.86 (0.49–1.52)

 

LVI

 Yes

1

0.047

 No

0.66 (0.44–0.99)

 

Tumor size (cm)

 ≤ 3

1

 

 > 3, ≤ 5

1.88 (1.14–3.08)

0.012

 > 5

2.31 (1.32–4.05)

0.003

Cycles of Chemotherapy

 ≤ 4

1

0.079

 > 4

0.70 (0.47–1.04)

 

PORT to the lung

 Yes

1

0.003

 No

1.81 (1.22–2.68)

 

PCI

 Yes

1

0.004

 No

1.89 (1.23–2.89)

 

Node levels

 Single-station N2

1

0.003

 Multiple-station N2

1.78 (1.21–2.61)

 

Node-spreading patterns

 Nonskip N2

1

0.103

 Skip N2

1.64 (0.90–3.01)

 

Subcarinal LN metastasis

 No

1

< 0.05

 Yes

2.08 (1.42–3.07)

 
  1. Abbreviations: PET positron emission tomography, SCLC small cell lung cancer, LVI lymphovascular invasion, PORT postoperative radiotherapy, PCI prophylactic cranial irradiation, HR hazard ratio, CI confidence interval