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Table 3 Multivariate analysis for overall survival

From: Prediction of lymph node status in completely resected IIIa/N2 small cell lung cancer: importance of subcarinal station metastases

Variables

Multivariate Analysis

HR(95% CI)

p value

Age

 < 60 years

1

0.411

 ≥ 60 years

1.19 (0.78–1.81)

 

Gender

 Male

1

0.420

 Female

1.34 (0.65–2.73)

 

Smoking status

 Smoker

1

0.520

 Never-smoker

0.81 (0.44–1.51)

 

Tumor endoscopy

 Peripheral

1

0.017

 Central

1.79 (1.11–2.90)

 

LVI

 Yes

1

0.420

 No

0.83 (0.53–1.29)

 

Tumor size (cm)

 ≤ 3

1

 

 > 3, ≤ 5

1.46 (0.84–2.52)

0.174

 > 5

1.65 (0.74–3.64)

0.216

PORT to the lung

 Yes

1

0.041

 No

1.53 (1.01–2.32)

 

PCI

 Yes

1

0.002

 No

2.10 (1.31–3.36)

 

Node levels

 Single-station N2

1

0.006

 Multiple-station N2

1.84 (1.19–2.84)

 

Subcarinal LN metastasis

 No

1

0.037

 Yes

1.57 (1.02–2.41)

 
  1. Abbreviations: SCLC small cell lung cancer, LVI lymphovascular invasion, PORT postoperative radiotherapy, PCI prophylactic cranial irradiation, HR hazard ratio, CI confidence interval