Table 1 Perioperative characteristics of patients with acute type A aortic dissection
Characteristics | Non-severe hypoxemia (n = 71) | Severe hypoxemia (n = 41) | p value |
|---|---|---|---|
Demographic data | |||
Age, year | 46.6 ± 11.1 | 49.5 ± 9.8 | 0.17 |
Female | 13 (18.3) | 16 (39.0) | 0.02 |
BMI, kg/m2 | 24.9 ± 3.3 | 28.5 ± 3.9 | < 0.001 |
Onset to surgery, hour | 48 (24, 120) | 30 (21, 72) | 0.19 |
Medical history | |||
Hypertension | 55 (77.5) | 34 (82.9) | 0.49 |
Diabetes mellitus | 1 (1.4) | 5 (12.2) | 0.05 |
Bicuspid aortic valve | 4 (5.6) | 0 | 0.31 |
Cerebrovascular disease | 3 (4.2) | 3 (7.3) | 0.79 |
Coronary artery disease | 2 (2.8) | 3 (7.3) | 0.53 |
Smoking history | 34 (47.9) | 21 (51.2) | 0.74 |
Marfan syndrome | 3 (4.2) | 4 (9.8) | 0.45 |
COPD | 1 (1.4) | 2 (4.9) | 0.63 |
Preoperative condition | |||
Lactate, mmol/L | 1.6 ± 0.7 | 1.9 ± 1.2 | 0.09 |
PaO2/FiO2, mmHg | 276 ± 87 | 249 ± 77 | 0.10 |
D-dimer, ug/mL | 1.1 (0.6, 2.8) | 2.3 (0.8, 3.1) | 0.05 |
White blood cell, × 103 cells/uL | 10.3 ± 3.5 | 12.8 ± 3.6 | < 0.001 |
Hemoglobin, g/dL | 137 ± 18 | 134 ± 17 | 0.28 |
sCr, umol/L | 83.2 ± 28.8 | 92.0 ± 29.9 | 0.13 |
Troponin I, ng/mL | 0.02 (0.00, 0.06) | 0.02 (0.00, 0.08) | 0.96 |
Aortic root size, mm | 41.1 ± 8.9 | 39.4 ± 4.9 | 0.21 |
Severe aortic regurgitation | 16 (22.5) | 8 (19.5) | 0.87 |
Ascend aorta size, mm | 45.8 ± 7.5 | 44.5 ± 6.7 | 0.36 |
Left ventricular ejection fraction, % | 62.5 ± 6.2 | 63.8 ± 5.9 | 0.31 |
Hemopericardium | 6 (8.5) | 5 (12.2) | 0.76 |
Operation details | |||
The duration of operation, hour | 8.0 ± 1.8 | 9.0 ± 1.7 | 0.004 |
CPB time, min | 200 ± 51 | 232 ± 59 | 0.004 |
Aortic cross clamp time, min | 120 ± 46 | 132 ± 35 | 0.14 |
The duration of HCA, min | 27.2 ± 9.8 | 28.0 ± 6.9 | 0.64 |
Nasopharyngeal temperature, °C | 23.2 ± 1.9 | 22.4 ± 1.5 | 0.02 |
Rectal temperature, °C | 25.5 ± 2.3 | 25.2 ± 2.3 | 0.47 |
Intraoperative blood loss, mL | 1449 ± 657 | 1578 ± 811 | 0.36 |
Intraoperative amount of plasma, mL | 400 (0, 400) | 500 (100, 800) | 0.004 |
Intraoperative amount of PRBCs, mL | 300 (0, 600) | 600 (150, 750) | 0.13 |
Postoperative outcomes | |||
Length of ICU, day | 1.7 (1.0, 3.0) | 6.0 (3.5, 11.0) | < 0.001 |
In-hospital mortality | 1 (1.4) | 5 (12.2) | 0.05 |
Reoperation for bleeding | 2 (2.8) | 7 (17.1) | 0.02 |
Postoperative dialysis | 6 (8.5) | 17 (41.5) | < 0.001 |
Low cardiac output syndrome | 2 (2.8) | 3 (7.3) | 0.53 |
Sepsis | 9 (12.7) | 8 (19.5) | 0.33 |
Paraplegia | 2 (2.8) | 2 (4.9) | 0.97 |
Cerebral infarction or bleeding | 0 | 7 (17.1) | 0.001 |