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Table 1 Perioperative characteristics of patients with acute type A aortic dissection

From: Increased risk for the development of postoperative severe hypoxemia in obese women with acute type a aortic dissection

Characteristics Non-severe hypoxemia (n = 71) Severe hypoxemia (n = 41) p value
Demographic data
 Age, year 46.6 ± 11.1 49.5 ± 9.8 0.17
 Female 13 (18.3) 16 (39.0) 0.02
 BMI, kg/m2 24.9 ± 3.3 28.5 ± 3.9 < 0.001
 Onset to surgery, hour 48 (24, 120) 30 (21, 72) 0.19
Medical history
 Hypertension 55 (77.5) 34 (82.9) 0.49
 Diabetes mellitus 1 (1.4) 5 (12.2) 0.05
 Bicuspid aortic valve 4 (5.6) 0 0.31
 Cerebrovascular disease 3 (4.2) 3 (7.3) 0.79
 Coronary artery disease 2 (2.8) 3 (7.3) 0.53
 Smoking history 34 (47.9) 21 (51.2) 0.74
 Marfan syndrome 3 (4.2) 4 (9.8) 0.45
 COPD 1 (1.4) 2 (4.9) 0.63
Preoperative condition
 Lactate, mmol/L 1.6 ± 0.7 1.9 ± 1.2 0.09
 PaO2/FiO2, mmHg 276 ± 87 249 ± 77 0.10
 D-dimer, ug/mL 1.1 (0.6, 2.8) 2.3 (0.8, 3.1) 0.05
 White blood cell, × 103 cells/uL 10.3 ± 3.5 12.8 ± 3.6 < 0.001
 Hemoglobin, g/dL 137 ± 18 134 ± 17 0.28
 sCr, umol/L 83.2 ± 28.8 92.0 ± 29.9 0.13
 Troponin I, ng/mL 0.02 (0.00, 0.06) 0.02 (0.00, 0.08) 0.96
 Aortic root size, mm 41.1 ± 8.9 39.4 ± 4.9 0.21
 Severe aortic regurgitation 16 (22.5) 8 (19.5) 0.87
 Ascend aorta size, mm 45.8 ± 7.5 44.5 ± 6.7 0.36
 Left ventricular ejection fraction, % 62.5 ± 6.2 63.8 ± 5.9 0.31
 Hemopericardium 6 (8.5) 5 (12.2) 0.76
Operation details
 The duration of operation, hour 8.0 ± 1.8 9.0 ± 1.7 0.004
 CPB time, min 200 ± 51 232 ± 59 0.004
 Aortic cross clamp time, min 120 ± 46 132 ± 35 0.14
 The duration of HCA, min 27.2 ± 9.8 28.0 ± 6.9 0.64
 Nasopharyngeal temperature, °C 23.2 ± 1.9 22.4 ± 1.5 0.02
 Rectal temperature, °C 25.5 ± 2.3 25.2 ± 2.3 0.47
 Intraoperative blood loss, mL 1449 ± 657 1578 ± 811 0.36
 Intraoperative amount of plasma, mL 400 (0, 400) 500 (100, 800) 0.004
 Intraoperative amount of PRBCs, mL 300 (0, 600) 600 (150, 750) 0.13
Postoperative outcomes
 Length of ICU, day 1.7 (1.0, 3.0) 6.0 (3.5, 11.0) < 0.001
 In-hospital mortality 1 (1.4) 5 (12.2) 0.05
 Reoperation for bleeding 2 (2.8) 7 (17.1) 0.02
 Postoperative dialysis 6 (8.5) 17 (41.5) < 0.001
 Low cardiac output syndrome 2 (2.8) 3 (7.3) 0.53
 Sepsis 9 (12.7) 8 (19.5) 0.33
 Paraplegia 2 (2.8) 2 (4.9) 0.97
 Cerebral infarction or bleeding 0 7 (17.1) 0.001
  1. Values are mean ± SD, n (%), or median (interquartile range)
  2. BMI body mass index, COPD chronic obstructive pulmonary disease, CPB cardiopulmonary bypass, HCA hypothermic circulatory arrest, ICU intensive care unit, PaO2/FiO2 arterial partial pressure of oxygen to fraction of inspired oxygen, PRBCs packed red blood cells, sCr serum creatinine