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Fig. 3 | Journal of Cardiothoracic Surgery

Fig. 3

From: Ischemia time impacts on respiratory chain functions and Ca2+-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury

Fig. 3

Degradation of mitochondrial membrane potential. Depolarization of ΔΨm due to CCCP-induced uncoupling of complex V. a Bars are normalized on IR0/30 to account for ischemia-driven relative changes of ΔΨm. b Points are normalized to their individual baseline. Arrow indicates the last pair of significantly different observations during reperfusion. Values are expressed as means ± standard error of the mean; *p ≤ 0.05, **p ≤ 0.01. ΔΨm: inner mitochondrial membrane potential; CCCP: carbonyl cyanide m-chlorophenyl hydrazine; JC1/J-aggregate: 5,50,6,60-tetrachloro-1,10,3,30-tetraethylbenzimidazolylcarbocyanine iodide

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