From: Long-term outcome after mitral valve replacement using biological versus mechanical valves
Total N = 324 | Biological MVR N = 265 | Mechanical MVR N = 59 | p-value | |
---|---|---|---|---|
Age in years | 69.0 [58.0–76.0] [324] | 71.0 [62.0–77.0] [265] | 56.0 [50.0–62.0] [59] | < 0.001 |
≤ 65 years, % | 133/324 (41.0) | 86/265 (32.5) | 47/59 (79.7) | < 0.001 |
Female gender, % | 161/324 (49.7) | 137/265 (51.7) | 24/59 (40.7) | 0.126 |
BMI (kg/m2) | 26.2 [23.2–29.0] [256] | 26.2 [23.0–28.9] [214] | 26.9 [23.2–31.7] [42] | 0.337 |
CV risk factors | ||||
Hypertension, % | 173/324 (53.4) | 147/265 (55.5) | 26/59 (44.1) | 0.112 |
Dyslipidemia, % | 52/324 (16.0) | 46/265 (17.4) | 6/59 (10.2) | 0.174 |
Comorbidity general | ||||
Diabetes mellitus, % | 35/324 (10.8) | 31/265 (11.7) | 4/59 (6.8) | 0.271 |
Kidney failure (Crea. > 2.26 mg/dL) | 8/324 (2.5) | 7/265 (2.6) | 1/59 (1.7) | 1.000 |
Stroke, % | 30/324 (9.3) | 27/265 (10.2) | 3/59 (5.1) | 0.221 |
COPD, % | 44/324 (13.6) | 39/265 (14.7) | 5/59 (8.5) | 0.206 |
PAD, % | 17/324 (5.2) | 16/265 (6.0) | 1/59 (1.7) | 0.328 |
Comorbidity cardiac | ||||
Atrial fibrillation, % | 126/324 (38.9) | 102/265 (38.5) | 24/59 (40.7) | 0.755 |
Coronary artery disease, % | 45/324 (13.9) | 41/265 (15.5) | 4/59 (6.8) | 0.081 |
Prior MI (≤90 days), % | 4/324 (1.2) | 3/265 (1.1) | 1/59 (1.7) | 0.554 |
Prior aortic valve replacement, % | 15/324 (4.6) | 11/265 (4.2) | 4/59 (6.8) | 0.489 |
Prior CABG, % | 25/324 (7.7) | 23/265 (8.7) | 2/59 (3.4) | 0.277 |
Prior pacemaker, % | 13/324 (4.0) | 11/265 (4.2) | 2/59 (3.4) | 1.000 |
NYHA class III/IV, % | 273/324 (84.3) | 225/265 (84.9) | 48/59 (81.4) | 0.498 |
CCS class III %a | 16/324 (4.9) | 12/265 (4.5) | 4/59 (6.8) | 0.505 |
Pulmonary hypertension, % | 56/324 (17.3) | 47/265 (17.7) | 9/59 (15.3) | 0.648 |
Emergency indication for surgery, % | 31/324 (9.6) | 23/265 (8.7) | 8/59 (13.6) | 0.249 |
Cardiac decompensation, % | 112/324 (34.6) | 95/265 (35.8) | 17/59 (28.8) | 0.304 |
Log EuroSCORE I (%) | 7.2 [3.5–15.6] [322] | 8.4 [3.6–17.5] [263] | 4.5 [2.9–8.0] [59] | < 0.001 |