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Table 1 Recipient baseline and clinical characteristics of ex vivo lung perfusion (EVLP) lung transplantations (LTX) and conventional LTx

From: Ten year follow-up of lung transplantations using initially rejected donor lungs after reconditioning using ex vivo lung perfusion

Variables

EVLP-LTx (n = 6)

Conventional-LTx (n = 15)

p-value

Weight (kg)

70.7 ± 19.3

59. 1 ± 7.9

0.060

Height (cm)

170.8 ± 11.8

169.9 ± 10.1

0.862

BMI

24.0 ± 5.3

20.5 ± 3.5

0.088

Male

3 (50%)

6 (40%)

0.523

Age (years)

54.1 ± 10.4

42.6 ± 14.8

0.100

Waiting list (days)

49.0 (7–174)

44 (4–389)

0.785

Pre-op Life support

 Mechanical ventilation

0 (0.00%)

1 (6.66%)

0.714

 ECMO

0 (0.00%)

1 (6.66%)

0.750

Major indication

  

0.407

 COPD

3 (50.00%)

5 (33.33%)

 

 AAT1

1 (16.66%)

0 (0.00%)

 

 PH

0 (0.00%)

1 (6.66%)

 

 CF

1 (16.66%)

7 (46.66%)

 

 PF

1 (16.66%)

1 (6.66%)

 

 LAM

0 (0.00%)

1 (6.66%)

 

Lab values

 FVC (liters)

2.0 ± 0.4

1.0 ± 0.6

0.540

 FEV1 (liters)

0.8 ± 10.4

54.1 ± 10.4

0.516

 6MWT (%)

39.6 ± 21.4

45.9 ± 25.1

0.600

 P-ALT (μkat/L)

0.41 ± 0.15

0.32 ± 10.4

0.181

 P-AST (μkat/L)

0.46 ± 0.12

0.41 ± 0.11

0.443

 P-creatinine (μmol/L)

64.4 ± 11.5

54.1 ± 15.8

0. 216

Tx-type

 SLTx

0 (0%)

0 (0%)

 

 DLTx

6 (100%)

15 (100%)

 

 HLTx

0 (0%)

0 (0%)

 

 Re-LTx

0 (0%)

0 (0%)

 
  1. Data are mean (SD), number (%), or median (range). The numbers are based on patients with available data. COPD, chronic obstructive pulmonary disease; AAT1, Alpha 1-antitrypsin deficiency; PH, pulmonary hypertension; CF, cystic fibrosis; PF, pulmonary fibrosis; LAM, Lymphangioleiomyomatosis; BMI, body-mass index; FVC, forced volume vital capacity; FEV1, forced volume expiratory capacity 1 s; 6MWT, 6-min walking test; AST, aspartate transaminase; ALT, alanine transaminase; SLTx, single-lung transplantation; DLTx, double-lung transplantation; HLTx, heart-lung transplantation; Re-LTx, re-lungtransplantation; ECMO, extracorporeal membrane oxygenation