Table 2 Estimated changes in ROTEM values and fibrinogen levels after four waves of blood product transfusion (intervention)
From: Interval changes in ROTEM values during cardiopulmonary bypass in pediatric cardiac surgery patients
Outcome | Intervention | Estimates | pb | |||
|---|---|---|---|---|---|---|
Na | Before (95% CI) | After (95% CI) | Change (95% CI) | |||
HEPTEM CT (sec) | Intervention I | 266 | 206.5 (194.2, 218.9) | 278.4 (264.6, 292.2) | 71.9 (59.8, 83.9) | < 0.001 |
Intervention II | 206 | 276.2 (264.9, 287.4) | 217.0 (199.7, 234.4) | −59.1 (−79.3, −39.0) | < 0.001 | |
Intervention III | 219 | 223.7 (204.0, 243.4) | 334.4 (301.1, 367.8) | 110.8 (77.7, 143.8) | < 0.001 | |
Intervention IV | 189 | 335.6 (248.1, 423.1) | 265.1 (182.5, 347.7) | −70.5 (−102.8, −38.2) | < 0.001 | |
HEPTEM MCF (mm) | Intervention I | 266 | 60.6 (58.5, 62.7) | 37.9 (35.6, 40.2) | −22.7 (−24.2, −21.2) | < 0.001 |
Intervention II | 205 | 38.6 (37.0, 40.2) | 55.0 (51.2, 58.8) | 16.4 (12.4, 20.4) | < 0.001 | |
Intervention III | 217 | 54.9 (51.2, 58.5) | 53.7 (50.4, 57.0) | −1.2 (−3.7, 1.4) | 0.380 | |
Intervention IV | 188 | 54.8 (48.1, 61.5) | 58.0 (51.5, 64.5) | 3.3 (1.1, 5.4) | 0.003 | |
FIBTEM MCF (mm) | Intervention I | 255 | 15.0 (13.0, 16.9) | 4.9 (3.1, 6.7) | −10.1 (−11.0, −9.2) | < 0.001 |
Intervention II | 196 | 5.1 (4.5, 5.6) | 7.9 (6.8, 9.0) | 2.9 (1.8, 4.0) | < 0.001 | |
Intervention III | 219 | 7.9 (6.7, 9.1) | 10.5 (9.4, 11.7) | 2.7 (2.0, 3.4) | < 0.001 | |
Intervention IV | 190 | 10.6 (9.1, 12.1) | 11.2 (9.8, 12.7) | 0.6 (−0.3, 1.6) | 0.197 | |
HEPTEM α (°) | Intervention I | 265 | 75.2 (73.1, 77.1) | 49.3 (45.5, 53.1) | −25.9 (−30.8, −21.0) | < 0.001 |
Intervention II | 204 | 51.2 (48.7, 53.7) | 73.3 (69.6, 76.5) | 22.1 (16.8, 27.4) | < 0.001 | |
Intervention III | 217 | 71.3 (67.4, 74.7) | 65.7 (63.0, 68.2) | −5.6 (−8.5, −2.7) | < 0.001 | |
Intervention IV | 188 | 66.1 (59.8, 71.6) | 69.6 (63.8, 74.3) | 3.4 (1.0, 5.9) | 0.005 | |