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Table 4 Risk Factors for Severe Gastrointestinal Complications

From: Morbidity and mortality of serious gastrointestinal complications after lung transplantation

  Gastrointestinal Complication
Variable Percentage P-value
Sex
 Male 58.8% 0.7446
Arterial hypertension 11.8% 0.8311
Diabetes Mellitus 17.6% 0.1239
Dyslipidemia 11.8% 0.9176
Etiology   0.5538
 Group 1 23.5%  
 Group 2 29.4%  
 Group 3 0%  
 Group 4 29.4%  
 Group 5 17.6%  
Bilateral lung transplant 70.6% 0.5435
Extracorporeal circulation 52.9% 0.4319
Extracorporeal membrane oxygenation 17.6% 0.1239
Tacrolimus 88.2% 0.4515
Mycophenolate 88.2% 0.4514
Azathioprine 5.9% 0.2096
Cyclosporine 11.8% 0.4964
Red blood cells transfusion 52.9% 0.543
Plasma transfusion 35.3% 0.2668
Platelet transfusion 41.2% 0.1561
Arrhythmias within 48 hours of transplantation 41.2% 0.0326
Hemodynamic instability over 48 hours 41.2% 0.8946
Low cardiac output 48 hours post-transplant 23.5% 0.0641
  Median  
Age 55.5 0.5778
Time Ischemia (minutes) > 400 290.7 0.1333
Multivariate analysis
  OR 95% CI P-value
Arrhythmias within 48 hours of transplantation 0.472 [0.141-1.586] 0.2248
ECMO 0.346 [0.064-1.883] 0.2196
Diabetes Mellitus 0.249 [0.047-1.321] 0.1424
Azathioprine 4.771 [0.524-43.460] 0.1656
Time Ischemia (minutes) > 400 0.927 [0.274-3.141] 0.1404
  1. Group 1: Idiopathic Pulmonary Fibrosis and usual interticial pneumonia. Group 2: Chronic Obstructive Disease and Alpha 1 Antitrypsin Deficiency. Group 3: Cystic fibrosis and bronchiectasis. Group 4: Primary arterial hypertension. Group 5: Other etiologies