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Table 4 Risk Factors for Severe Gastrointestinal Complications

From: Morbidity and mortality of serious gastrointestinal complications after lung transplantation

 

Gastrointestinal Complication

Variable

Percentage

P-value

Sex

 Male

58.8%

0.7446

Arterial hypertension

11.8%

0.8311

Diabetes Mellitus

17.6%

0.1239

Dyslipidemia

11.8%

0.9176

Etiology

 

0.5538

 Group 1

23.5%

 

 Group 2

29.4%

 

 Group 3

0%

 

 Group 4

29.4%

 

 Group 5

17.6%

 

Bilateral lung transplant

70.6%

0.5435

Extracorporeal circulation

52.9%

0.4319

Extracorporeal membrane oxygenation

17.6%

0.1239

Tacrolimus

88.2%

0.4515

Mycophenolate

88.2%

0.4514

Azathioprine

5.9%

0.2096

Cyclosporine

11.8%

0.4964

Red blood cells transfusion

52.9%

0.543

Plasma transfusion

35.3%

0.2668

Platelet transfusion

41.2%

0.1561

Arrhythmias within 48 hours of transplantation

41.2%

0.0326

Hemodynamic instability over 48 hours

41.2%

0.8946

Low cardiac output 48 hours post-transplant

23.5%

0.0641

 

Median

 

Age

55.5

0.5778

Time Ischemia (minutes) > 400

290.7

0.1333

Multivariate analysis

 

OR

95% CI

P-value

Arrhythmias within 48 hours of transplantation

0.472

[0.141-1.586]

0.2248

ECMO

0.346

[0.064-1.883]

0.2196

Diabetes Mellitus

0.249

[0.047-1.321]

0.1424

Azathioprine

4.771

[0.524-43.460]

0.1656

Time Ischemia (minutes) > 400

0.927

[0.274-3.141]

0.1404

  1. Group 1: Idiopathic Pulmonary Fibrosis and usual interticial pneumonia. Group 2: Chronic Obstructive Disease and Alpha 1 Antitrypsin Deficiency. Group 3: Cystic fibrosis and bronchiectasis. Group 4: Primary arterial hypertension. Group 5: Other etiologies