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Table 1 Perioperative factors of patients with or without postoperative pneumonia by univariate analysis (n = 727)

From: Excessive intravenous crystalloid infusion after video-assisted thoracoscopic surgery lobectomy is associated with postoperative pneumonia

VariableEntire cohort
(n = 727)
Univariate analysis
Postoperative pneumonia
(n = 143)
No postoperative pneumonia
(n = 584)
P-value
Age (year)62.9 ± 11.063.9 ± 11.862.6 ± 10.70.211
Gender (female/male)391/33681/62310/2740.444
Weight (kg)61.6 ± 9.963.0 ± 10.361.2 ± 9.80.057
Body mass index (kg/m2)23.2 ± 2.923.9 ± 2.923.0 ± 2.80.001
Body mass index grading< 0.001
 < 24.0 kg/m2465 (64.0%)71 (49.7%)394 (67.5%) 
 ≥ 24.0 kg/m2262 (36.0%)72 (50.3%)190 (32.5%) 
Smoking, pack-years10.9 ± 23.78.3 ± 16.511.6 ± 25.10.477
Diabetes mellitus64 (8.8%)10 (7.0%)54 (9.2%)0.394
Hypertension206 (28.3%)43 (30.1%)163 (27.9%)0.608
Coronary heart disease9 (1.2%)0 (0.0%)9 (1.5%)0.218
History of lung surgery or chest trauma16 (2.2%)2 (1.4%)14 (2.4%)0.750
Preoperative renal insufficiency4 (0.6%)1 (0.7%)3 (0.5%)0.584
Forced expiratory volume in 1 s (percentage of predicted value)91.1 ± 17.5%89.9 ± 17.1%91.4 ± 17.6%0.364
Forced vital capacity (percentage of predicted value)91.7 ± 15.9%89.0 ± 14.8%92.4 ± 16.1%0.023
Peak expiratory flow (percentage of predicted value)67.1 ± 23.7%67.3 ± 27.1%67.0 ± 22.8%0.555
Surgical lobe0.004
 Left lung lobe279 (38.4%)40 (28.0%)239 (40.9%) 
 Right lung lobe448 (61.6%)103 (72.0%)345 (59.1%) 
Amount of intraoperative fluids, mL
 Total1529.2 ± 412.11473.4 ± 396.41542.8 ± 415.00.071
 Crystalloid1235.5 ± 385.01179.7 ± 354.01249.1 ± 391.30.053
 Colloid293.7 ± 255.9293.7 ± 247.0293.7 ± 258.30.999
 Blood000
Intraoperative bleeding, mL48.3 ± 34.054.2 ± 43.346.8 ± 31.10.020
Intraoperative urine output, mL406.7 ± 326.7376.9 ± 315.0414.0 ± 329.30.224
Length of operation, min131.7 ± 35.6128.2 ± 35.0132.5 ± 35.70.191
Length of anaesthesia, min159.1 ± 37.5158.8 ± 37.6159.2 ± 37.50.908
Total intravenous crystalloid infusion in the postoperative 24 h, mL1273.5 ± 277.51321.2 ± 287.61261.8 ± 274.00.022
Total intravenous crystalloid infusion grading in the postoperative 24 h0.006
 < 1000 mL128 (17.6%)26 (18.2%)102 (17.5%) 
 1000 to < 1500 mL461 (63.4%)77 (53.8%)384 (65.8%) 
 ≥ 1500 mL138 (19.0%)40 (28.0%)98 (16.8%) 
Total intravenous colloid infusion in the postoperative 24 h, mL000
Postoperative pathology0.097
 Malignant tumour n634 (87.2%)123 (86.0%)511 (87.5%) 
 Benign tumour, n10 (1.4%)0 (0.0%)10 (1.7%) 
 Benign non-inflammatory disease, n7 (1.0%)0 (0.0%)7 (1.2%) 
 Inflammatory disease, n76 (10.5%)20 (14.0%)56 (9.6%) 
Second operation within 30 days after surgery1 (0.1%)0 (0.0%)1 (0.2%)1.000
Postoperative prolonged air leak, n17 (2.3%)6 (4.2%)11 (1.9%)0.120
  1. Values are presented as mean ± standard deviation, n, or n (%)