Fig. 3From: High shear stress suppresses proliferation and migration but promotes apoptosis of endothelial cells co-cultured with vascular smooth muscle cells via down-regulating MAPK pathwayDetection of ECs proliferation. a. MTT assay was used to detect ECs proliferation. Significant differences were observed among the group Con, the group SS1, and the group SS1 + U0126 (p < 0.001). And, significant differences were observed among the group Con, the group SS1, and the group SS1+ PD98059 (p < 0.001). b. BrdU assay was used to detect ECs proliferation. Significant differences were observed among the group Con, the group SS1, and the group SS1 + U0126 (p < 0.001). And, significant differences were observed among the group Con, the group SS1, and the group SS1+ PD98059 (p < 0.001)Back to article page