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Table 3 Risk factors associated with postoperative sSIRS

From: Severe systemic inflammatory response syndrome in patients following Total aortic arch replacement with deep hypothermic circulatory arrest

Variables

Univariable analysis

Multivariable analysis

OR

95% CI

P

OR

95% CI

P

Male

1.56

1.17–2.09

0.003

   

Age (years)

      

 <60

1.37

1.06–1.76

0.015

2.93

2.01–4.28

< 0.001

 ≥ 60

1

     

BMI (kg/m2)

 Underweight (< 18.5)

0.22

0.05–1.02

0.054

   

 Normal weight (18.5–24.9)

0.23

0.06–0.83

0.024

   

 Overweight (25.0–29.9)

0.33

0.09–1.17

0.086

   

 Obese (30.0–39.9)

0.39

0.10–1.46

0.161

   

 Morbidly obese (≥ 40)

1

 

0.011

   

Hyperlipidemia

1.18

0.90–1.56

0.231

   

Glucose (mmol/l)

  

 (≤ 140)

1.61

0.53–4.87

0.397

   

 (141–170)

2.21

0.72–6.83

0.168

   

 (171–200)

1.58

0.45–5.50

0.473

   

 (> 200)

1

 

0.161

   

Moderate-severe anemia

1.51

0.80–2.84

0.200

   

Serum creatinine

1.66

1.23–2.24

0.001

1.61

1.18–2.20

0.003

Smoking

1.02

0.79–1.33

0.868

   

COPD

1.62

0.54–4.93

0.392

   

Cerebral infarction

0.77

0.47–1.28

0.320

   

Dialysis prior to surgery

1.24

0.55–2.79

0.609

   

Hypertension

0.98

0.73–1.32

0.915

   

Dissection

1.15

0.64–2.04

0.647

   

Coronary disease

0.69

0.42–1.14

0.151

2.00

1.15–3.48

0.015

Cardiac surgery history

0.78

0.67–1.70

0.784

   

Aortic regurgitation

0.99

0.76–1.28

0.920

   

LVEF

0.98

0.96–1.01

0.118

   

CPB (minutes)

 < 200

1

     

 ≥ 200

1.59

1.21–2.09

0.001

1.63

1.23–2.18

0.001

Ulinastatin

0.63

0.48–0.83

0.001

0.69

0.51–0.93

0.015

Dexmedetomidine

0.36

0.24–0.54

<0.001

0.36

0.23–0.56

< 0.001

  1. sSIRS Severe systematic inflammatory systematic syndrome, OR Odds ration, CI Confidential interval, BMI Body mass index, COPD Chronic obstructive pulmonary disease, LVEF Left ventricular ejection fraction, CPB Cardiopulmonary disease