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Table 5 Deterministic sensitivity and probabilistic analysis

From: Preconditioning with levosimendan reduces postoperative low cardiac output in moderate-severe systolic dysfunction patients who will undergo elective coronary artery bypass graft surgery: a cost-effective strategy

Deterministic sensitivity analysisLCO incidenceCost per patient (€)Mean ICU stay per patient (days)Mean PO ward stay per patient (days)Patients with no complications
(% of total)
Intervention (Levosimendan)Base case14,792.332.506.4653.85
LCO 18% [4]14,562 [13,741-14,879]2.35 [1.8–3]6.22 [5.7–7.8]55.01 [52.87–57.87]
LCO 6% [17]12,757 [12,172-14,892]2.07 [1.4–2.3]5.63 [4.9–7.5]61.23 [55.69–68.71]
No interventionBase case17,006.945.706.4031.71
LCO 35% [16]16,511 [15,061- 16,773]5.3 [4.1–6.9]6.1 [4.9–6.5]35.22 [32.6–38.03]
LCO 25% [4]15,825 [14,988- 16,260]4.8 [3.5.-5.7]5.9 [4.8–6.3]38.6 [35.7–41.32]
Probabilistic analysisCost per patient (€)Mean ICU stay (days)Mean PO
ward stay (days)
Patients with no complications (% of total)
Intervention (Levosimendan)14,401 [13,368-14,971]2.39 [1–3.9]6.23 [4.2–8.34]51.8 [47.34–53.02]
No intervention16,652 [16,004- 17,212]5.4 [3.8–7.1]6.17 [4.03–8.22]29.98 [27.91–32.4]
Difference2251   
  1. €: euro, LCO: Low Cardiac Output, PO: postoperative, ICU: Intensive Care Unit, [95% CI]
  2. [4] Ref. 4 (Mehta RH at al.) [16]. Ref 16 (Pieri M et al.) [17]. Ref 17 (Desai PM et al.)