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Table 2 Univariate and multivariate Cox regression analysis for cancer specific survival in patients ESCC with stage T1-3N0M0 (Cox regression’s method is Forward: LR)

From: Preoperative squamous cell carcinoma antigen and albumin serum levels predict the survival of patients with stage T1-3N0M0 esophageal squamous cell carcinoma: a retrospective observational study

Characteristics

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Gender (male vs. female)

0.722

0.456–1.141

0.163

   

Age (continuous)

1.020

0.997–1.043

0.082

   

Smoking history (no vs. yes)

1.608

1.059–2.443

0.036

0.283

Drinking history (no vs. yes)

1.681

1.150–2.459

0.007

1.878

1.275–2.765

0.001

Primary tumor location

 Upper (reference)

1

   

 Middle

0.728

0.334–1.585

0.424

   

 Lower

1.023

0.688–1.522

0.910

   

pT stage (T1 vs. T2 vs. T3)

1.445

1.102–1.894

0.008

1.551

1.167–2.061

0.002

SCC-Ag (continuous)

1.227

1.105–1.361

< 0.001

1.200

1.083–1.330

0.001

Albumin (continuous)

0.939

0.889–0.991

0.022

0.945

0.896–0.997

0.038

LNs (continuous)

0.984

0.969–0.999

0.040

0.982

0.967–0.997

0.020

Tumor length (continuous)

1.070

0.960–1.194

0.222

   

Anastomotic leakage (no vs. yes)

1.078

0.579–2.009

0.812

   

Chylothorax (no vs. yes)

1.066

0.149–7.640

0.949

   

Respiratory complications (no vs. yes)

0.880

0.324–2.389

0.803

   

Cardiovascular complications (no vs. yes)

1.118

0.276–4.529

0.876

   
  1. The factors in the univariate analyses with P value less than 0.05 would be took in account into multivariate analyses. LNs the number of lymph nodes removed in surgery, HR hazard ratio, CI confident interval