Table 5 Predictors of in-hospital mortality of IE patients
From: Infective endocarditis at a tertiary-care hospital in China
Survisors (n = 349) | Death (n = 32) | p | OR | Multivariable regression | ||
|---|---|---|---|---|---|---|
Age (older than 70) | 19 | 8 | 0.002 | 4.583 (1.861, 11.285) | 3.887 (1.072,14.096) | 0.039 |
Sex (Male/Female) | 230/119 | 25/7 | 0.175 | 0.541 (0.227,1.288) | ||
Rheumatic heart disease | 21 | 2 | 1.000 | 1.041 (0.233,4.656) | ||
Degenerative valve disease | 49 | 1 | 0.100 | 0.197 (0.026,1.480) | ||
Congenital heart disease | 66 | 2 | 0.090 | 0.286 (0.067,1.226) | ||
Hypertrophy cardiomyopathy | 7 | 1 | 0.508 | 1.576 (0.188,13.226) | ||
History of IE | 9 | 1 | 0.589 | 1.219 (0.149,9.936) | ||
Hypertension | 64 | 13 | 0.005 | 3.047 (1.431,6.488) | ||
DM | 28 | 6 | 0.053 | 2.646 (1.005,6.965) | ||
Immunocompromised state | 15 | 7 | 0.001 | 6.235 (2.328,16.694) | ||
dialysis | 2 | 3 | 0.005 | 17.948 (2.882,111.761) | ||
cancer | 9 | 4 | 0.017 | 5.397 (1.563,18.635) | ||
Health care associated IE | 37 | 11 | 0.001 | 4.417 (1.974,9.881) | ||
Native valve involvement | 322 | 30 | 1.000 | 1.28 (0.285,5.549) | ||
Prosthetic valve involvement | 24 | 2 | 1.000 | 1.108 (0.250,4.916) | ||
Cardiac device-related IE | 3 | 0 | 1.000 | 0.991 (0.982,1.001) | ||
Fever | 336 | 31 | 1.000 | 0.834 (0.106,6.587) | ||
New murmur | 142 | 15 | 0.574 | 1.286 (0.622,2.660) | ||
Heart failure | 52 | 18 | 0.000 | 7.343 (3.441,15.671) | 7.955 (2.966,21.338) | 0.000 |
Vascular phenomena | 144 | 19 | 0.061 | 2.081 (0.996,4.348) | ||
stroke | 71 | 17 | 0.000 | 4.212 (2.009,8.830) | 4.190 (1.669,10.519) | 0.002 |
Immunological phenomena | 113 | 5 | 0.070 | 0.387 (0.145,1.031) | ||
Viridans group streptococci | 136 | 7 | 0.059 | 0.43990.185,1.042) | ||
Staphylococcus aureus | ||||||
MRSA | 9 | 1 | 0.589 | 1.219 (0.149,9.936) | ||
MSSA | 18 | 2 | 0.680 | 1.226 (0.271,5.538) | ||
CNS | 11 | 1 | 1.000 | 0.991 (0.124,7.933) | ||
Enterococcus faecalis | 10 | 1 | 1.000 | 1.094 (0.135,8.826) | ||
Streptococcus bovis | 5 | 1 | 0.411 | 0.451 (0.051,3.979) | ||
HAECK | 12 | 0 | 0.610 | 0.966 (0.947,0.985) | ||
Rickettsia | 4 | 0 | 1.000 | 0.989 (0.977,1.000) | ||
TB | 1 | 0 | 1.000 | 0.997 (0.992,1.003) | ||
Fungi | 3 | 3 | 0.009 | 11.931 (2.304,61.787) | ||
Polymicrobial | 8 | 2 | 0.201 | 2.842 (0.577,13.988) | ||
Vegetation | 298 | 27 | 0.798 | 0.924 (0.340,2.511) | ||
Aortic valve | 117 | 10 | 0.847 | 0.901 (0.413,1.966) | ||
Mitral valve | 127 | 12 | 1.000 | 1.049 (0.496,2.216) | ||
Tricuspid valve | 31 | 1 | 0.500 | 0.331 (0.044,2.507) | ||
Pulmonary valve | 14 | 0 | 0.618 | 0.960 (0.940,0.981) | ||
Multi valve involvement | 34 | 6 | 0.128 | 2.138 (0.822,5.559) | ||
New severe mitral regurgitation | 48 | 7 | 0.198 | 1.756 (0.720,4.283) | ||
New severe aortic regurgitation | 59 | 6 | 0.806 | 1.134 (0.447,2.877) | ||
Medical therapy | 81 | 23 | 0.000 | 0.118 (0.053,0.266) | 6.854 (2.632,17.848) | 0.000 |