Sex-specific risk factors for early mortality and survival after surgery of acute aortic dissection type a: a retrospective observational study

Table 4 Pre- and intraoperative variables with univariate association to 30-d-mortality (p-values ≤0.10) and interaction between sex and risk factors (logistic regression analysis, p-values)

Variable	All Patients (n = 368)	Male (n = 242)	Female (n = 126)	Sex-specific Interaction
Total cases	368	242	126	–
Female gender	0.545
Age, years	0.100	0.971	0.026	0.123
Logistic EuroSCORE I (%)	< 0.001	0.003	< 0.001	0.599
Cardiopulmonary resuscitation 48 h preoperative	< 0.001	< 0.001	< 0.001	0.226
Cardiogenic shock		0.037		0.266
Intubated	< 0.001	0.001	0.004	0.821
Chronic obstructive pulmonary disease			0.018	0.059
Arterial hypertension	0.010	0.004		0.198
Peripheral arterial disease			0.019	0.083
Coronary heart disease	< 0.001		< 0.001	0.009
Previous percutaneous coronary intervention	0.007		< 0.001	0.005
Previous cardiac surgery	0.005		0.006	0.999
Diabetes mellitus type II	0.059			0.928
Hyperlipoproteinemia			0.009	0.005
Creatinine (μmol/l) preoperative^a	0.007	0.001	0.051	0.334
Chronic renal insufficiency			0.039	0.017
Ascending aorta prostheses (mm)	0.088			0.434
Length of surgery (min)	0.001	0.006	0.060	0.231
Cardiopulmonary bypass time (min)	< 0.001	0.001	0.034	0.855
Surgical procedure
Additional coronary artery bypass graft	< 0.001	0.018	0.003	0.508
Partial arch replacement	0.061	0.036		0.232
TEVAR/EVAR		0.050		0.998
Number of RBC, (U)	< 0.001	0.008	0.001	0.658
Number of platelets, (U)	< 0.001	0.048	0.001	0.198

TEVAR/EVAR, (thoracic) endovascular aortic repair, RBC Red blood cell concentrate (unit)
^a19% missing values; italic text, inverse association; bold text, p-values ≤0.05

ISSN: 1749-8090