Variables | PDA ligation (n = 134) | Non-ligation (n = 99) | p value |
---|---|---|---|
Maternal characteristics | |||
Maternal age, years | 32.58 ± 4.30 | 33.29 ± 4.10 | 0.205 |
Mother’s education level | 0.946 | ||
High, n (%) | 9 (6.7) | 6 (6.1) | |
Intermediate, n (%) | 88 (65.7) | 67 (67.7) | |
Low, n (%) | 37 (27.6) | 26 (26.3) | |
GDM | 10 (7.5) | 10 (10.1) | 0.488 |
PIH | 9 (6.7) | 16 (16.2) | 0.031 |
PPROM | 56 (41.8) | 42 (42.4) | > 0.999 |
Histologic chorioamnionitis | 104 (77.6) | 63 (63.6) | 0.027 |
Neonate characteristics | |||
Gestational age, weeks | 26.27 ± 2.28 | 27.37 ± 1.90 | < 0.001 |
Birth weight, grams | 882.05 ± 226.61 | 1053.23 ± 244.76 | < 0.001 |
Length | 33.69 ± 4.59 | 35.96 ± 3.36 | < 0.001 |
Head circumference | 24.60 ± 3.10 | 25.58 ± 2.37 | 0.010 |
Cesarean section | 98 (73.1) | 81 (81.8) | 0.157 |
Male sex | 69 (51.5) | 41 (41.8) | 0.183 |
Apgar score at 1 min | 2.10 ± 1.30 | 2.73 ± 1.33 | < 0.001 |
pgar score at 5 min | 4.58 ± 1.67 | 5.40 ± 1.55 | < 0.001 |
Antenatal corticosteroids | 92 (68.7) | 73 (73.7) | 0.467 |
Postnatal corticosteroids | 57 (42.5) | 31 (31.3) | 0.101 |
Age at PDA closure, days | 15.57 ± 8.94 | 8.10 ± 2.71 | < 0.001 |
Body weight at surgical ligation | 911.87 ± 270.16 | – | – |
IVH | 50 (37.3) | 43 (43.4) | 0.417 |
IVH grade II | 8 (6) | 3 (3) | 0.241 |
IVH grade ≥ III | 21 (15.7) | 17 (17.2) | 0.858 |
PVL | 10 (7.5) | 9 (9.1) | 0.809 |
Culture-proven sepsis | 83 (61.9) | 55 (55.6) | 0.347 |
NEC | 12 (9.0) | 10 (10.1) | 0.823 |
NEC stage ≥ III | 41 (30.8) | 22 (22.2) | 0.180 |
BPD | 74 (55.6) | 44 (44.9) | 0.112 |
ROP | 80 (60.2) | 54 (55.1) | 0.501 |
Days on mechanical ventilator | 30.62 ± 18.63 | 16.20 ± 14.55 | < 0.001 |
Days of oxygen therapy | 68.70 ± 52.01 | 49.41 ± 28.20 | 0.001 |
TPN days | 44.44 ± 25.64 | 36.59 ± 21.21 | 0.014 |
Hospital days | 96.00 ± 40.44 | 79.89 ± 28.56 | 0.001 |
PDA size | 2.13 ± 0.84 | 1.68 ± 0.92 | 0.001 |
PDA ductal diameter > 2.0 mm | 70 (52.2) | 22 (22.2) | < 0.001 |
Deaths | 1 (0.7) | 2 (2) | 0.576 |