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Table 3 Outcomes in the unmatched and propensity score matched cohorts

From: Mid-term outcomes of Sapien 3 versus Perimount Magna Ease for treatment of severe aortic stenosis

  Unmatched cohort Propensity score matched cohort
Outcomes Sapien 3
(N = 689)
Perimount Magna Ease
(N = 1311)
p-value Sapien 3
(N = 308)
Perimount Magna Ease
(N = 308)
p-value
In-hospital death 8 (1.2) 26 (2.0) 0.177 4 (1.3) 11 (3.6) 0.092
Stroke 9 (1.3) 48 (3.7) 0.003 1 (0.3) 11 (3.6) 0.006
Vascular complications    < 0.0001    < 0.0001
 Minor 18 (2.6) 0   8 (2.6) 0  
 Major 58 (8.4) 13 (1.0)   29 (9.4) 2 (0.6)  
Annulus rupture 2 (0.3) 0   1 (0.3) 0  
Aortic dissection/rupture 2 (0.3) 7 (0.5) 0.727 1 (0.3) 1 (0.3) 1.000
Coronary ostium occlusion 2 (0.3) 2 (0.2) 0.612 1 (0.3) 2 (0.6) 1.000
Acute kidney injury stages 2–3 5 (0.7) 72 (5.5) < 0.0001 1 (0.3) 24 (7.8) < 0.0001
Postoperative dialysis 2 (0.3) 20 (1.5) 0.012 0 7 (2.3) 0.015
Moderate/severe paravalvular regurgitation 8 (1.2) 10 (0.8) 0.370 6 (1.9) 4 (1.3) 0.754
Severe bleeding* 14 (2.1) 282 (21.9) < 0.0001 4 (1.3) 88 (29.0) < 0.0001
Reoperation for bleeding 14 (2.0) 129 (9.8) < 0.0001 7 (2.3) 33 (10.7) < 0.0001
Red blood cell transfusion, units 0.3 (1.1) 2.6 (3.4) < 0.0001 0.27 (1.0) 3.2 (3.5) < 0.0001
Postoperative IABP or ECMO 0 11 (0.8) 0.020 0 3 (1.0) 0.249
Atrial fibrillation 269 (39.0) 733 (55.9) < 0.0001 102 (33.1) 200 (64.9) < 0.0001
Permanent pacemaker implantation 52 (7.5) 47 (3.6) < 0.0001 28 (9.1) 16 (5.2) 0.064
Hospital stay, days 4.0 ± 3.4 7.7 ± 5.5 < 0.0001 4.1 ± 3.7 8.4 ± 6.8 < 0.0001
  1. Categorical values are reported as counts and percentages. Continuous variables are reported as mean and standard deviation. ECMO extracorporeal membrane oxygenation, IABP intra-aortic balloon pump; * = transfusion of more than 4 units of red blood cells and/or reoperation for bleeding